The Tim Ferriss Show

#819: Rhonda Patrick, Ph.D. — Protocols for Fasting, Lowering Dementia Risk, Reversing Heart Aging, Using Sauna for Longevity (Hotter is Not Better), and a Few Supplements That Might Actually Matter

1731 snips
Jul 23, 2025
Rhonda Patrick, Ph.D., a biomedical scientist and founder of FoundMyFitness, shares her expertise on optimizing healthspan. She explores various fasting protocols and their benefits, emphasizing their role in cellular repair and disease prevention. The conversation dives into the significance of VO2 max for longevity and the surprising cognitive benefits of creatine. Patrick also discusses nutritional strategies to mitigate dementia risk, the implications of alcohol on brain health, and the importance of transparency in supplement quality for improving overall health.
Ask episode
AI Snips
Chapters
Transcript
Episode notes
00:00 / 00:00

Parents’ Supplements & Health

  • Rhonda Patrick's parents took multivitamins and vitamin D to support cognition and general health as they age. - Her dad's Parkinson's has progressed slowly, which they attribute at least partially to these interventions.
00:00 / 00:00

Take Sulforaphane for Aging

  • Take sulforaphane from broccoli sprouts to activate NRF2 and boost stress response genes. - This promotes antioxidant, anti-inflammatory pathways and enhances glutathione production for brain protection.
00:00 / 00:00

Intermittent Fasting Benefits

  • Intermittent fasting (e.g., 16-8) improves metabolic health by reducing calorie intake and enhancing glucose regulation. - It also activates ketosis and repair processes like autophagy, which clears cellular damage.
Get the Snipd Podcast app to discover more snips from this episode
Get the app