Immune 52: B cell boot camp with Gabriel Victora

1

Introduction

00:00 • 2min

2

Shucapio's PhD at the Whitehead Fellows

01:44 • 3min

3

The Importance of Neuroscience in Immunology

05:08 • 2min

4

The Evolution of Antibodies

07:00 • 3min

5

The Darwinian B Cell Squid Game

09:44 • 2min

6

The Darwinian Process of Antibodies

11:45 • 3min

7

The Importance of Clonal Dynamics in Antibodies

14:20 • 2min

8

The Effects of Journal Centers on Antigen Receptors

16:06 • 2min

9

Clonal Dynamics in Mice

17:51 • 5min

10

The Evolution of Inter-Clone Competition

22:37 • 3min

11

The Brainbow: A Mouse That Picks a Color

25:11 • 3min

12

Clonal Burst: How High Affinity B Cells Migrate

27:45 • 2min

13

The Different Patterns of Germinal Centers in the Brain

29:19 • 2min

14

The Germinal Centers That Drain the Gut Are Dominating the Competition

31:29 • 3min

15

The Memory B Cells in the SARS-CoV-2 Vaccine

34:11 • 2min

16

The Effects of Brango on Secondary Germinal Centers

36:01 • 2min

17

The Evolution of Memory in Mouse Cells

37:52 • 2min

18

The Bottleneck in Antigen Recognition

39:39 • 2min

19

The Role of Memory in the Recall Response

41:13 • 3min

20

The Importance of Memory in Humans

43:57 • 2min

21

How to Make High Affinity Antibodies to HIV

46:24 • 2min

22

The Effects of Environment on Immune Responses in Mice

48:19 • 2min

23

How to Induce a Germinal Center in a Mouse

50:12 • 3min

24

T-Independent Germinal Centers

52:50 • 2min

25

The Importance of Multiple Doses in SARS-CoV-2 Antigens

54:36 • 2min

26

The Broadening of Memory Cells After a Third Boost

56:45 • 2min

27

The Effect of Multiple Boosts on Memory and Antibodies

58:22 • 2min

28

The Effect of Vaccination on Germal Centers Memory

01:00:30 • 2min

29

The Role of Secondary Germinal Centers in Memory B Cell Regeneration

01:02:13 • 2min

30

The Importance of Starting Fresh

01:03:46 • 2min

31

The Effects of Immunization on the Stem Response to Influenza

01:05:29 • 2min

32

The Evolution of Immunology

01:07:05 • 2min

33

The Evolution of the Mammalian System

01:08:54 • 2min

34

The Effects of Omicron on the Immune System

01:11:12 • 2min