How to Induce a Germinal Center in a Mouse

Some things don't work in the same way as it would in a human because the mice are too clean. The feature part is that you're not confounded by history, as I am with my moles. There are studies where you want to mimic closely humans where dirty mice are going to be a better model. But in other cases, if you want to go down to the basics, you might want to stick with the cleanest mice you can get.