Immune

From the 2024 Society for Leukocyte Biology meeting, Cindy and Brianne sit down with Justin Wilson to talk about how he got into research and his more recent studies on innate immune sensors and the interaction between the gut microbiome and inflammation related to inflammatory bowel disease and cancer. Hosts: Cindy Leifer and Brianne Barker Guest: Justin Wilson Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Francisella tularensis undermining macrophage defenses (Infect Immunity) AIM2 suppressing colon cancer (Nature Med) NLRP12 regulates gut microbiota homeostasis (Cell Host Microbe) Oral bacteria and carcinogenesis connection (Microbiol Mol Bio Rev) Society for Leukocyte Biology Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Steph talks about identification of gut bacteria that can digest protective mucosal antibodies and Vincent covers a new paper on Zika virus that implicates fetal phagocytes in brain invasion, which may provide insight into the devastating microcephaly outcome of infection during pregnancy. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Gut bacteria induce mucosal immunodeficiency (Science) Contribution of fetal mononuclear phagocytes to Zika virus neuroinvasion (Cell) TWiV468 discusses Zika and brain slice infection model. Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

From the 2024 Society for Leukocyte Biology meeting, Immune talks with Holger Heine about the discovery of immune recognition of bacterial lipopolysaccharide and innate immunity to organisms within the kingdom Archaea. Hosts: Cindy Leifer and Brianne Barker Guest: Holger Heine Become a patron of Immune! Links for this episode MicrobeTV Discord Server TLR8 recognizes human gut-associated archaeon (Front Immunol) The human archaeome and its relevance for health and disease (FEBS) Structural insights into TLR4 recognition of synthetic LPS mimetics (Nature Comm) Society for Leukocyte Biology Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

In this episode, researcher Kim Klonowski and parasitologist David Peterson from the University of Georgia dive into exciting immunology topics. They discuss how type one interferons in the thymus influence T cell development and autoimmunity. The conversation shifts to the challenges of developing malaria vaccines for pregnant women, exploring funding hurdles and the role of key proteins. They also reflect on their podcast journey, emphasizing the importance of making science accessible while sharing personal tales from their academic experiences.

From the 2024 Society for Leukocyte Biology meeting, Immune talks with Amy Hise about her career in science, her current research using mouse models for investigating fungal immunity and navigating the challenges of being a mom in science. Hosts: Cindy Leifer and Brianne Barker Guest: Amy Hise MicrobeTV Discord Server Mouse model for testing drugs to treat Candida fungal infection Inflammasomes in Aspergillosis Society for Leukocyte Biology Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Content in this podcast should not be construed as medical advice.

In this engaging discussion, James Lederer, an associate professor specializing in neutrophil research, and Elizabeth Kovacs, an expert on aging and lung inflammation, delve into the intricate responses of the immune system to trauma. They explore fascinating topics such as the role of natural immune mice in research and how gut, lungs, and brain function together during injury. Additionally, they discuss the effects of alcohol on burn patients and the implications of aging on lung health, shedding light on the complexities of immunity.

Immune Booster #10 HIV in the brain with Amanda Brown March 18, 2025 From the The Society for Leukocyte Biology 2024 conference at Michigan State University, Cindy and Brianne sit down with Amanda Brown from Johns Hopkins School of Medicine to talk about her career and the research of her laboratory on mechanisms of neuroinflammation in disease, especially during HIV infection. Hosts: Cindy Leifer and Brianne Barker Guest: Amanda Brown Society for Leukocyte Biology Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Content in this podcast should not be construed as medical advice.

Immune discusses how non-neutralizing antibodies can still be protective…intracellularly, and a technically innovative paper that uses Lipstic to label antigen-presenting cells responsible for gut tolerance to food antigens. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Non-neutralizing antibodies protect against CCHFV (Nat Comm) APC-T cell interactions drive immune responses to food (Science) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv    

Immune describes the use of bespoke antibodies to characterize immune cell populations in cave nectar bats, and co-option of retrotransposons to activate hematopoietic stem cells and erythropoiesis. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Immune cells in cave nectar bats (Cell Rep) Cave nectar bat colony (J Am Asso Lab An Sci) Retrotransposons activate erythropoiesis (Science) TLRs and ERVs (Immunity) Letters read on Immune 88 Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Delve into the fascinating world of basophils and their surprising role in regulating lung inflammation and asthma. Learn about the complexities of lupus as autoreactive T-cells target neoself-antigens, emphasizing the condition's tricky diagnosis. Discover the crucial functions of MHC molecules in immune responses and the implications of invariant chain research in understanding autoimmunity. The hosts also explore the relationship between stress and immune response, revealing how it can trigger autoimmune diseases like lupus.