Immune 97: Bystander B cells go bananas

Cindy and Steph discuss a paper that challenges the textbook dogma that B cells must first bind to an antigen for antibody affinity maturation to occur, and a snippet on dysfunctional T cells during bacterial vaginosis.

Hosts: Cindy Leifer and Steph Langel

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Links for this episode

• MicrobeTV Discord Server
• Somatic hypermutation in non-specific B cells (Immunity 2025)
• Dysfunctional T cells during bacterial vaginosis (J Clin Invest 2025)
• Time stamps by Jolene Ramsey. Thanks!

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Information on this podcast should not be construed as medical advice.