The Germinal Centers That Drain the Gut Are Dominating the Competition

We have looked extensively at the mesenteric lymph nodes. These germinal centers are potentially responding to hundreds of thousands of different antigens, right? Now, actually find a solution, a unique solution and they become dominated by one clone. So it seems like the germination centers are just so wired to do this competition that even when they're not really supposed to, they still do it. And this is something we are trying to work out.