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Immune 52: B cell boot camp with Gabriel Victora

Immune

CHAPTER

The Evolution of Inter-Clone Competition

In a paper, you show that there are several hundred or a thousand clones of B-cells. And so then, so it's not so basically like a germinal center is responding to 20 antigens,. I'm sorry, no, 60 antigens, 20 germinal centers times three clones. And you're realizing no, it's more like 100 per per germinal. So the effect that that had on us was it, it shifted our thoughts from this journal center mechanics and onto inter-clonal competition between clone specifics.

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