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Immune 52: B cell boot camp with Gabriel Victora

Immune

CHAPTER

The Different Patterns of Germinal Centers in the Brain

There are different stromal cells in the lymph node called follicular dendritic cells that secrete a chemokine CXCl13. Because they're patchy, they sort of attract patches of B-cell around them. There are many different factors, including CXCl 13, but also S1 gr2 is a receptor for a single lipid. And other receptors, they're important, that really constrain the B-cells to one single germinal center.

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