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The Role of Memory in the Recall Response
The two sort of double key that needs to be turned to unleash the B-cell are antigen design and T-cells. So it really, designing antigen design is going to target these clones that are going to mobilize to the journal center. There are the ones that are good to start with; they tend to dominate the response. These tend to become much better and tend to really dominate the recall response.