Regenerative Health with Max Gulhane, MD cover image

Regenerative Health with Max Gulhane, MD

30. Tucker Goodrich: How Seed Oils Oxidise Cardiolipin and Damage Your Mitochondria

Jun 16, 2023
01:52:39

Podcast summary created with Snipd AI

Quick takeaways

  • Mitochondrial dysfunction is a common thread in chronic diseases, influenced by the fatty acids we consume.
  • Cardiolipin, a molecule in mitochondria, can be damaged by excessive linoleic acid, leading to compromised energy production.

Deep dives

Mitochondria: The Powerhouse of Disease

Mitochondria are essential for energy production, but they also play a critical role in many aspects of health and disease. Mitochondrial dysfunction is a common thread in chronic diseases such as diabetes, Parkinson's, and Alzheimer's. The structure and function of mitochondria are influenced by the fatty acids we consume, particularly polyunsaturated fats like linoleic acid. When the balance of these fats in the mitochondria is disrupted, it can lead to oxidative stress and damage, compromising the energy production process. Linoleic acid, if not regulated properly, can react with other fats in the mitochondria, leading to auto-oxidation and the release of toxins. This mitochondrial dysfunction can trigger various cell death processes, such as apoptosis and necrosis, causing health issues. It is crucial to maintain a proper balance of fatty acids and minimize the intake of vulnerable fats to support healthy mitochondrial function and prevent chronic diseases.

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