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30. Tucker Goodrich: How Seed Oils Oxidise Cardiolipin and Damage Your Mitochondria

Regenerative Health with Max Gulhane, MD

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The Role of the 4HNE Marker in Glucose Detachment

4HNE is produced by the oxidation of linoleic acid and cardiolipin molecules. It's not a proxy for consumption, it's a proxy for oxidation of the fat. HNE damages pyruvate dehydrogenase and causes it to become less optimally functional if not entirely dysfunctional. One study that I looked at examined all the proteins in the cell that are damaged by HNE.

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