4min chapter

Regenerative Health with Max Gulhane, MD cover image

30. Tucker Goodrich: How Seed Oils Oxidise Cardiolipin and Damage Your Mitochondria

Regenerative Health with Max Gulhane, MD

CHAPTER

The Role of the 4HNE Marker in Glucose Detachment

4HNE is produced by the oxidation of linoleic acid and cardiolipin molecules. It's not a proxy for consumption, it's a proxy for oxidation of the fat. HNE damages pyruvate dehydrogenase and causes it to become less optimally functional if not entirely dysfunctional. One study that I looked at examined all the proteins in the cell that are damaged by HNE.

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