Siim Land Podcast

#330 The 7 Tenets of Aging - Dr Sandra Kaufmann

7 snips
Oct 6, 2022
Ask episode
AI Snips
Chapters
Transcript
Episode notes
INSIGHT

Sirtuins Are More Nuanced Than SIRT1

  • Sirtuins beyond SIRT1 (notably SIRT3 and SIRT6) are central to mitochondrial and DNA maintenance.
  • Targeting specific sirtuins gives more granular control of aging processes than one-size-fits-all approaches.
INSIGHT

Mitochondrial Pores Drive Cellular Decline

  • Mitochondrial pores (MPTP) open more with age and flood cells with toxic contents, driving organ decline.
  • Controlling the mitochondrial permeability transition pore is emerging as a high-impact longevity target.
ADVICE

Make Exercise And Diet Non-Negotiable

  • Prioritize regular aerobic exercise and strength work to maintain muscle and overall system resilience.
  • Combine consistent exercise with a healthy diet to support every aging tenant.
Get the Snipd Podcast app to discover more snips from this episode
Get the app