In a lively discussion, Tim Gray, a biohacker and health optimization expert, delves into the importance of sleep quality, revealing dietary tweaks that can help. He tackles food sensitivities and their link to autoimmunity, providing insights on NMN and CoQ10 safety. Tim shares the optimal dosage for astaxanthin as a potent antioxidant and discusses strategies to boost testosterone naturally. They also explore the roles of magnesium and choline for cognitive health, and how AI can customize health recommendations for individuals.

Dr. Sandra Kaufmann, an anti-aging expert, shares her unique rating system for evaluating longevity supplements. She explores fascinating topics like the benefits of astaxanthin, NAD boosters, and curcumin, discussing how they affect cellular health. The conversation highlights disappointing supplements like resveratrol and emphasizes the importance of personalized approaches to supplementation. Kaufmann also addresses essential compounds like melatonin and taurine, urging listeners to make informed choices for lasting wellness.

Dr. Michael Lustgarten, an expert in bloodwork analysis, reveals how tracking crucial blood markers can extend longevity. He discusses the importance of understanding biomarkers beyond just cholesterol and glucose, and their relationship with chronic diseases. Lustgarten emphasizes the risks of low cholesterol in older adults and calls for meticulous health tracking. He also shares insights on the impact of protein safety and the significance of monitoring health metrics to improve well-being over time.

Get Bon Charge red light therapy for 15% off: https://boncharge.com/pages/siimlandTimestamps: 00:38 Nick’s PhD and autophagy research 02:33 What is autophagy 03:53 Autophagy and longevity 08:05 Bon Charge Sponsorship 08:55 Where autophagy comes from 11:40 What triggers autophagy 18:15 mTOR and longevity 20:15 Should you eat a lower protein diet 25:45 Supplements for autophagy 28:35 Metformin 32:35 Acarbose 34:25 Rapamycin 36:35 Speed of aging tests 43:00 Longevity supplements 50:05 Nick’s opinions on diet 56:35 Nick’s nutrition, exercise and supplement plan 01:01:10 Importance of sleepPhysionic YouTube channel: https://www.youtube.com/@Physionic/

BioPrime oral BPC157 with code SIIM10 for 10% discount - Get 3 month supply for best effects: https://www.bioprimesupplements.com/index.php?route=product%2Fproduct&product_id=53&tracking=g8PrbVPWwr3K1a42mbbnslSqmty6fFgjT3YxDU0MAXwf18eL4MBMHgSQgFBSv3FrTimestamps:00:25 Dr Karli’s training in cell therapies07:00 BioPrime Supplements Sponsorship07:55 Why do people develop pain disorders10:00 Importance of exercise for orthopedic longevity14:30 Injuries from exercise19:30 Does nutrition play a role in joint disorders23:40 Stem cells for orthopedics35:30 Converging functional medicine and regenerative medicine42:05 When do you need surgery44:25 PRP – platelet rich plasma48:10 PRP and stem cells for prevention54:10 Peptides for joints59:40 Rapid fire round: which joint problem which therapy 01:07:40 Daily exercises to prevent joint painDr David Karli Instagram: https://www.instagram.com/davidkarli/

Get Bon Charge red light therapy for 15% off: https://boncharge.com/pages/siimlandTimestamps: 00:41 Mark’s backstory 05:41 How the body and mind connected 11:40 How to balance your nervous system 20:30 How to stimulate the vagus nerve 23:10 Nutrition and gut health 27:10 Blood markers for stress 30:00 You need to focus on both mental and physical health 40:20 How to deal with health anxiety 46:30 Mark’s free webinar 49:35 Core pillars of thriving as a humanDr Mark's Free Webinar Thrive Essentials: https://theschoolofbiohacking.com/programs/thrive-essentials/ref/5/

Dr. Tyler Panzner, an expert in genetics and personalized medicine, shares insights on how our genes influence supplement effectiveness. He reveals the genetic factors affecting caffeine and creatine metabolism. The discussion also explores the complexities of supplements like glycine and the impact of diet on food sensitivities. Tyler highlights the importance of individualized nutrition strategies, particularly regarding vitamin D and omega-3s, while addressing common misconceptions in the realm of health supplements.

Dr. Olli Sovijärvi, an expert in resilience and longevity, co-authored "The Resilient Being." He dives deep into the fascinating overlap between stress resilience and longevity. Olli explains how controlled exposure to stressors, like sauna and cold therapy, can bolster health. He discusses the importance of adaptogens, like Reishi, for stress management, and how early encounters with nature enhance immune function. Personal anecdotes heighten the connection between facing challenges and cultivating resilience for a longer, healthier life.

Nathan Cheng, who left his PhD in physics to dive into longevity research, shares his ambitious vision for extending human lifespan. He discusses revolutionary ideas like body replacement, organ cloning, and brain emulation. Cheng explores bioengineering advancements that could halt aging and the ethical dilemmas surrounding organ replacement. He highlights innovative approaches to advocacy, fostering community engagement in longevity, and the cultural shift needed to prioritize anti-aging initiatives. It's a fascinating journey into the future of human health!

Dr. Alexis Ortega, MD, a specialist in skin anti-aging and aesthetics, shares his vast knowledge on skincare routines and treatments. He emphasizes the need for effective anti-aging practices and analyzes the impact of sun damage on skin health. The conversation highlights the importance of retinoids, microneedling, and advanced technologies like exosomes in rejuvenation. Dr. Ortega also discusses key products, such as sunscreens and copper peptides, while recommending age-defying supplements like collagen and hyaluronic acid for better skin elasticity.