Siim Land Podcast

Greg Potter, PhD, is a circadian rhythm and time-restricted eating expert who dives into the fascinating science of our body's internal clocks and their impact on aging. He discusses how circadian clock dysfunction contributes to age-related changes and highlights the connection between genetic factors and longevity. Potter explains the effects of shift work, artificial light, and the benefits of aligning with your natural rhythms. He also delves into the role of melatonin and offers tips for optimizing morning routines to promote health as we age.

Dr. Paul Robbins, a leading researcher in aging and biochemistry at the University of Minnesota, dives into cellular senescence and its fascinating role in aging. He discusses the promising benefits of eliminating senescent cells for health and lifespan extension. The conversation covers groundbreaking senolytic therapies, gene therapies, and lifestyle strategies to enhance well-being as we age. Robbins also tackles the potential of compounds like rapamycin and the importance of immune function in longevity, making a compelling case for innovations in anti-aging research.

In this engaging discussion, Greg Potter, a nutrition expert and Chief Science Officer at a supplement startup, dives into the intriguing relationship between diet and longevity. He emphasizes the importance of what, how much, and when we eat, revealing how meal timing can significantly affect metabolic health. Potter contrasts low-carb and plant-based diets, advocating for personalized nutrition strategies tailored to individual needs. Their conversation sheds light on the role of protein in overall well-being and tackles nutrition misinformation in the age of social media.

The discussion delves into a detailed comparative analysis of health biomarkers between two individuals. It highlights intriguing differences in fitness, body composition, and metabolic health. Listeners will learn about inflammation and immune markers, alongside cardiovascular and kidney health indicators. The conversation also touches on hormone levels and experimental tests for longevity. Plus, a fascinating look at the PhenoAge biological age test adds depth to the exploration of how one can rewind their biological clock.

Dive into a detailed ranking of over 100 supplements for 2025, from the highly praised methylated B vitamins to the controversial resveratrol. Discover the health benefits of intriguing options like sulforaphane, ashwagandha, and NAC. The evaluation covers efficacy, risks, and specific populations who might benefit most. Plus, learn about the importance of probiotics tailored to individual gut health. Unpack which supplements truly stand out for longevity and metabolic support.

Dr. Joe Zundell, a dedicated cancer biologist, delves into groundbreaking cancer research and innovations in treatment. He discusses how lifestyle choices, such as exercise and stress management, significantly influence cancer risks. The impact of environmental toxins is examined, including how living near golf courses may elevate health risks. Zundell elaborates on early cancer detection and the essential differentiation between benign and malignant tumors, while also addressing the potential role of certain supplements in cancer prevention.

Greg Potter, PhD, an expert in sleep and nutrition, and Nicolas Verhoeven, PhD, a specialist in exercise physiology, discuss the vital role of exercise in health. They explore the dangers of a sedentary lifestyle and how varying exercises combat chronic diseases. The conversation touches on the importance of VO2 max for longevity, the balance between cardio and resistance training, and humorous workout mishaps. Listeners will appreciate practical advice on personalized fitness routines and the significance of integrating movement into daily life.

Dr. Anil Bajnath, a physician specializing in precision medicine and detoxification, dives deep into the science behind detoxing. He discusses how the body naturally detoxifies and the crucial roles of sweating and hydration in this process. Anil busts myths about detox scams and emphasizes the need for a holistic approach beyond just the liver. He shares insights on supplements, gut health, and practical detox strategies tailored to combat modern toxins, including mold and microplastics, providing listeners with actionable advice for better health.

Kristi Storoschuk, a PhD candidate at Queen's University specializing in muscle physiology, dives into the cardio debate between HIIT and Zone 2 training. Discover the unique mitochondrial benefits that Zone 2 offers and why it's favored by athletes. Kristi explains optimal training volumes and the importance of balancing both training types. She discusses her personal shift in workout strategy based on research insights, emphasizing adaptability and the necessity of personalized fitness regimes for achieving better health and performance.

Dr. Nicolas Verhoeven, aka Physionic, and Dr. Greg Potter, both PhD experts in longevity supplements, dive deep into the world of dietary nutraceuticals. They discuss underrated supplements like taurine and ergothioneine, and tackle the importance of timing for supplement intake. The duo explores the science behind omega-3s, vitamin D, and the potential of new players like nobilitin and trace lithium. Their insights also touch on the interplay between supplements and genetics, and how these factors can shape health and aging.