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Lifespan with Dr. David Sinclair
The Science of Keeping the Brain Healthy | Episode 7
Feb 16, 2022
01:01:48
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Quick takeaways
- A Mediterranean diet can protect and reverse cognitive decline in the aging brain.
- Exercise improves executive function and promotes the growth of new brain cells.
Deep dives
The Role of Diet, Exercise, and Supplements in Slowing Brain Aging
A Mediterranean diet has been shown to protect the brain from aging and may even reverse cognitive decline. Exercise, particularly aerobic and strength training, improves executive function and helps grow new brain cells. Metformin, an AMPK activator, has been found to improve cognitive function and prevent dementia in studies on fish, mice, and humans. NAD boosters, such as NADH and NR, can increase NAD levels in the brain and have been shown to slow brain aging and improve cognitive function. Supplements like resveratrol and terrestilbine also have potential benefits.
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