The Stronger By Science Podcast

Meta-Analysis Errors; Motivation and Behavior Change

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Dec 12, 2022
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INSIGHT

Meta-Analyses Depend On Data And Methods

  • Meta-analyses are powerful but only as reliable as their data and calculations.
  • A flawed meta can mislead even if it sits atop the evidence hierarchy.
ANECDOTE

The First Meta-Analysis Was A Public Feud

  • Eric recounts the historical spat between Almroth Wright and Karl Pearson over the typhoid vaccine.
  • Pearson's early meta analysis suffered from poor data and limited computation, altering public health judgment.
INSIGHT

Top-Cited Meta Studies Still Contain Errors

  • Cadlec et al. screened the 20 most-cited strength meta-analyses for errors and found many problems.
  • Using highly cited studies likely understates current error prevalence given improving methods over time.
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