The Rich Roll Podcast Dr. Rhonda Patrick On Why Exercise Fuels The Brain, How Microplastics Poison The Body, & The Science Of Fitness
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Jan 20, 2025 
Dr. Rhonda Patrick, a renowned scientist and founder of FoundMyFitness, sheds light on how exercise supercharges brain function, overturning myths around lactate. She delves into the mounting crisis of microplastics, discussing their alarming effects on health and ways to mitigate exposure. Rhonda emphasizes vigorous exercise’s role in enhancing neuroplasticity and reducing the risk of cognitive decline. Additionally, she explores the intertwining relationship between gut health, sleep quality, and metabolic fitness, providing practical tips for a healthier lifestyle.
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Lactate: A Signaling Molecule
- Lactate, produced during vigorous exercise, isn't a waste product.
- It signals muscle adaptation and boosts brain-derived neurotrophic factor (BDNF).
Cardiorespiratory Fitness and Longevity
- Cardiorespiratory fitness, often measured as VO2 max, is a strong longevity marker.
- It surpasses other biomarkers like epigenetic age and blood glucose levels.
Improving VO2 Max
- To improve cardiorespiratory fitness, incorporate vigorous intensity exercise.
- Many people don't respond to moderate-intensity exercise alone for VO2 max improvement.
