Siim Land Podcast #359 Reversing Biological Aging and Extending Lifespan - Matt Kaeberlein PhD
Apr 28, 2023
Chapters
Transcript
Episode notes
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Introduction
00:00 • 5min
The Role of Genetics in Aging
05:12 • 3min
The First 150 Year Old Has Already Been Born
08:41 • 3min
The Disconnect Between Genetic Engineering and Longevity
11:12 • 2min
The Genetics of Centenarian Longevity
13:00 • 3min
The Importance of Genetic Change in Longevity
15:51 • 2min
The Importance of Lifestyle in Longevity
18:19 • 3min
The Complexity of Human Aging
21:46 • 2min
The Importance of Caloric Restrictions in Humans
24:10 • 2min
The Effect of Calorie Restrictions on Pathogen Exposure
26:16 • 2min
The Effects of Caloric Restrictions on Life Expectancies
28:13 • 2min
The Effects of Protein Restrictions on Lifespan in Mice
30:25 • 3min
The Effects of Calorie Restrictions on Lifetime Extension
33:04 • 3min
The Effects of Intermittent Fasting on Longevity
35:54 • 4min
The Role of Rapamycin in Calorie Restrictions
40:07 • 3min
Rapamycin and Longevity
42:54 • 3min
The Effects of Rapamycin on Organ Transplant Patients
46:17 • 4min
The Dog Aging Project
50:32 • 2min
The Role of Epigenetic Clocks in Predicting Aging
52:55 • 4min
The Biohacker Crowd and the Epigenetic Tests
57:18 • 3min
The Importance of Blood Work in Epigenetic Testing
01:00:12 • 2min
Epigenetic Reprogramming Can Reverse Aging
01:02:37 • 4min
Reversing Aging With Exercise
01:06:28 • 3min
The History of Extreme Lifestyle Modification
01:09:40 • 3min
The Benefits of Low Protein Caloric Restrictions
01:12:12 • 3min
The Biology of Aging
01:15:00 • 2min
How to Be Happy and Happy Every Day
01:16:42 • 3min