#359 Reversing Biological Aging and Extending Lifespan - Matt Kaeberlein PhD
Siim Land Podcast
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The Effects of Calorie Restrictions on Lifetime Extension
Time-restricted feeding and intermittent fasting. When you don't control for calories, you can get lifespan extension from those studies but they're always calorically restricted. Protein restriction falls into this category as well. Sometimes mice that are protein restricted will actually eat more total calories than mice that are getting the control diet. So again, I think that supports the idea that total calories is really what's most important at least in mice.
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