Muscle injury, repair and aging with Dr Abigail Mackey

Dr Glenn McConell chats with Associate Professor Abigail Mackey from the University of Copenhagen. Abigail is an expert on muscle injury, repair and aging.  They discussed these plus the protective effect of repeated bouts of eccentric exercise, whether it’s smart to take anti-inflammatories after injury, different types and areas of injuries, causes of injuries, treatment of muscle injuries, muscle innervation, exercise and age and more.  

0:00. Introduction and how got into the area 

4:32. Composition of skeletal muscle. Muscle biopsies, mixed muscle, single muscle fibers etc. 

8:31. Muscles response to injury. Satellite cells. 

12:12. Muscle regeneration after injury. Biopsies, eccentric exercise and electrical stimulation. 

15:41. Protective effect of repeated eccentric exercise. Don’t get sore when repeated bouts. 

19:42. Smart to take anti-inflammatories after injury? 

23:20. Different types and areas of injury. 

28:25. Causes of injuries.

31:30. Treatment of muscle injuries. 

33:54. Treatment of chronic tendon injuries. 

36:23. Aging and injuries. Get injuries more frequently. Less motor neurons and less muscle fibers with age. 

45:54. Muscle innervation, exercise and age. 

58:58. Do you find what you expect when do studies? So-called negative findings. 

1:07:35. How elevated creatine kinase when no damage?  

Inside Exercise brings to you the who's who of exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.  

The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.  

He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).  

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