Valter Longo, PhD | Fasting for Metabolic Health & Longevity | The Metabolic Link Ep.6

16 snips

Feb 28, 2023

Ask episode

AI Snips

Chapters

Transcript

Episode notes

INSIGHT

FMD Improves Diabetes Markers Versus Mediterranean Diet

Monthly five-day fasting-mimicking diet (FMD) cycles reduced A1c, insulin resistance, and medication needs in diabetic patients compared to a Mediterranean diet control.
The FMD also lowered hypertension medication use, showing broad metabolic benefits beyond calorie change.

INSIGHT

FMD Shows Promise In Alzheimer's Models And Elders

FMD cycles reduced Alzheimer's pathology and cognitive decline in two mouse models and showed promising pilot compliance in ~80-year-old human participants.
Elderly patients tolerated monthly FMD cycles over a year, supporting feasibility in older populations.

INSIGHT

FMD Can Sensitize Tumors To Immunotherapy

In mice, combining FMD with immunotherapy made non-immunogenic tumors more visible and responsive to checkpoint blockade by increasing oxidative stress and antigenicity.
This mechanistic synergy supports clinical trials pairing FMD with immunotherapies and adjuncts like vitamin C.

Get the Snipd Podcast app to discover more snips from this episode

Get the app

On this week’s episode of The Metabolic Link, we’re sitting down with world-renowned Fasting and Longevity Researcher, Valter Longo, PhD, to explore a variety of topics related to metabolic health including the impact of protein consumption on longevity, the latest research on the fasting mimicking diet in diabetes and Alzheimer’s, the future of metabolic therapies, and how both our host of The Metabolic Link, Dr. Dominic D'Agostino, and Dr. Longo utilize fasting and approach healthy eating in their own lives.

Dr. Valter Longo has thirty years of experience in the field of longevity and healthy eating. He is the Director of the Longevity Institute at the University of Southern California – Leonard Davis School of Gerontology, Los Angeles, and the Director of the Longevity and Cancer Program at the IFOM, The Italian Foundation for Cancer Research (FIRC) Institute of Molecular Oncology in Milan, Italy. He is the author of the best seller “The Longevity Diet” and the 2 Italian books “Alla tavola della longevità” (“At the Table of Longevity”), and “La longevità inizia da bambini” (“Longevity Begins in Childhood”). Professor Longo is also the scientific director of the Create Cures Foundation and the Valter Longo Foundation. In 2018, TIME Magazine named Professor Longo as one of the 50 most influential people in health care for his research on fasting-mimicking diets as a way to improve health and prevent diseases.

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

Find us on social:

Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.