

The Metabolic Link
Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field
Welcome to The Metabolic Link, a medical and science podcast that explores the common thread of metabolism in health and disease. Join Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field as they dive into the latest research on metabolic health and therapy alongside some of the world’s leading experts. They'll also discuss how this science is being applied in the real world. This is where science meets society.
Episodes
Mentioned books

22 snips
Nov 4, 2025 • 1h 6min
Dr. Nina Teicholz | America's Metabolic Decline: The High-Cost of Low Fat | The Metabolic Link Ep 80
Dr. Nina Teicholz, a science journalist and author of 'The Big Fat Surprise,' unpacks the flawed foundation of low-fat dietary guidelines. She discusses how Ancel Keys' controversial research shaped U.S. nutrition policy and the dire metabolic consequences of replacing fat with carbs. Nina reveals the influence of the food industry on health guidelines, the detrimental effects of seed oils, and the evolution of cholesterol recommendations. With a call to embrace saturated fat again, she shares hope for a dietary shift towards more evidence-based nutrition.

11 snips
Oct 21, 2025 • 1h 9min
Metabolic Therapy for Pets: The Future of Veterinary Medicine | Dr. Loren Nations | The Metabolic Link Ep. 79
Dr. Loren Nations, a board-certified veterinarian with over 30 years in integrative medicine, reveals how personal tragedy spurred a shift towards metabolic therapies for pets. He discusses alarming rates of obesity in cats and dogs and advocates for ketogenic diets as a solution. Delving into gut health, he shares strategies for restoring the microbiome and stresses the importance of nutrition over processed foods. Dr. Nations also outlines innovative cancer treatments using hyperbaric oxygen and targeted supplements, showcasing a transformative approach to veterinary care.

Oct 8, 2025 • 47min
Can a Ketogenic Diet Improve Sleep Apnea? | Dr. Jonathan Jun | The Metabolic Link Ep. 78.
What if the food you eat could change the way you breathe at night? In this episode, recorded live at The Metabolic Health Summit, Dr. Jonathan Jun reveals how metabolism and sleep-disordered breathing are deeply connected, and why shifting from carbs to fat might improve more than just your waistline.Dr. Jonathan Jun, a leading researcher on obesity hypoventilation syndrome (OHS) and obstructive sleep apnea (OSA), walks us through the groundbreaking KETOHS trial, where a ketogenic diet was tested for its effects on carbon dioxide retention, sleep apnea severity, and metabolic health. The findings suggest ketosis may do more than promote weight loss - it could directly enhance respiratory efficiency and sleep quality in patients with OHS and OSA.From a long-forgotten 1976 fasting study to modern clinical data, this lecture reframes the connection between diet, breathing, and metabolism, revealing how nutritional ketosis might transform respiratory and metabolic medicine.Questions Answered in This Episode:Why does fuel choice (carbs vs. fat) matter for breathing in people with sleep-disordered breathing?What exactly happens in obesity hypoventilation syndrome (OHS), and why is it more dangerous than OSA alone?Why did a 1976 starvation ketosis study inspire modern trials on ketogenic diets for OSA/OHS?How was the KETOHS trial designed to isolate the effects of ketosis itself (not just weight loss)?Can a ketogenic diet improve sleep apnea severity even without CPAP therapy?Is the improvement in CO₂ clearance explained only by weight loss, or something else?What metabolic changes accompany ketogenic therapy in this context?This episode will change the way you see the link between diet and breathing, and may open new doors for treating some of the toughest sleep and metabolic disorders.Special thanks to the sponsors of this episode:✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here. ✅ ZocDoc - Find and instantly book a top-rated doctor here.✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

12 snips
Oct 1, 2025 • 1h 23min
The Metabolic Approach to Treating Food Addiction | Dr. Tro Kalayjian | The Metabolic Link Ep. 77
Dr. Tro Kalayjian, a board-certified internist and obesity medicine specialist, discusses revolutionary ideas about food addiction. He delves into whether food addiction should be classified as a true addiction and shares insights from his TOWARD intervention, revealing that nearly half of participants saw reduced addiction symptoms. The conversation covers the compelling links between dopamine signaling, ultra-processed foods, and the difficulties of treatment. Tro also highlights the importance of scalable, real-world solutions for overcoming food-related compulsions.

43 snips
Sep 16, 2025 • 1h 19min
Built to Last: Muscle, Longevity, and Training Smarter | Dr. Andy Galpin | The Metabolic Link Ep. 76
Dr. Andy Galpin, a human performance scientist with a PhD in Human Bioenergetics, dives into the vital role of muscle as metabolic armor. He discusses the synergy between muscle mass, cardio fitness, and bone density in promoting longevity. Listeners learn when fasted training benefits women, how kids can safely engage in resistance training, and myths about strength training. Galpin also shares personalized strategies for recovery and emphasizes the importance of tailored approaches for women, particularly concerning hormonal influences and metabolic health.

20 snips
Sep 2, 2025 • 1h 26min
Redefining Recovery: A Metabolic Approach to Plastic Surgery | Cameron Chesnut, MD | The Metabolic Link Ep.75
Dr. Cameron Chesnut, a facial plastic surgeon known for his innovative approach, discusses how he revolutionizes recovery in plastic surgery through metabolic science. He reveals the benefits of ketones and hyperbaric oxygen for faster healing and emphasizes the elimination of opioids post-surgery. Chesnut also shares insights on optimizing recovery with nutrition, advanced anesthetic techniques, and regenerative therapies like red light and fat grafting enhancements. This approach not only prioritizes natural results but also transforms the entire surgical experience.

57 snips
Aug 19, 2025 • 1h 3min
Reversing Alzheimer's Disease | Dr. Dale Bredesen | The Metabolic Link Ep.74
Dr. Dale Bredesen, a leading neurologist and researcher, reveals groundbreaking insights into Alzheimer’s disease. He challenges the notion of a single-cause approach, emphasizing the need for a systems-based strategy. Bredesen discusses his ReCODE Protocol, which has shown promise in reversing cognitive decline. He highlights the importance of early detection, the role of diet and toxins, and calls for a holistic approach to treatment. His insights offer hope and a proactive path forward in the fight against dementia.

21 snips
Aug 4, 2025 • 1h 9min
Healing the Brain: A Metabolic Approach to Mental Illness | Erin Bellamy, PhD | The Metabolic Link Ep.73
In this engaging discussion, Dr. Erin Bellamy, a Chartered Psychologist and Metabolic Psychiatry Practitioner, shares insights into ketogenic metabolic therapy for mental illness. She explains how KMT addresses brain hypometabolism and neuroinflammation, offering hope for conditions like PTSD and ADHD. Dr. Bellamy discusses a transformative case study showcasing the impact of tailored nutritional protocols. With a focus on personalized health approaches, she emphasizes the importance of individualized treatment and community support in enhancing mental well-being.

7 snips
Jul 22, 2025 • 1h 2min
Diabetes: Nutrition & Cardiometabolic Health | Andrew Koutnik, PhD | The Metabolic Link Ep.72
In this insightful discussion, Andrew Koutnik, a research scientist at the Sansom Diabetes Research Institute, sheds light on the surprising stagnation in blood sugar control for Type 1 diabetes despite technological advancements. He reveals groundbreaking findings on carbohydrate intake and its effects on glycemic management. Dr. Koutnik also explores the long-term safety of low-carb diets through a unique decade-long case study, emphasizing nutrition as a crucial, yet underutilized, tool in diabetes care and its impact on cardiovascular health.

19 snips
Jul 8, 2025 • 1h 3min
Journal Club: Prenatal Sugar Exposure & a Metabolic Therapy Framework for Brain Cancer | Ep.71
Discover groundbreaking research on prenatal sugar exposure and its long-term effects on health, including reduced risks of type 2 diabetes and hypertension. Learn about the historical context of sugar rationing and its impact on childhood health. The discussion also highlights challenges parents face in managing sugar consumption and the need for systemic policy changes. Additionally, explore innovative ketogenic metabolic therapies for glioblastoma and the importance of collaborative approaches in cancer treatment, emphasizing the integration of diet and exercise.


