

The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life.
Episodes
Mentioned books

Dec 23, 2021 • 34min
Kindness: The Win-Win Superpower – Jamil Zaki, Ph.D. & Leon Logothetis : 888
Jamil Zaki, Ph.D., a Stanford psychology professor researching kindness and empathy, joins Leon Logothetis, a world-renowned adventurer and motivational speaker known as 'The Kindness Guy.' They explore how kindness is a learnable skill that transforms personal well-being and fosters connection. The duo shares insights on the societal impacts of kindness, practical adventures to enhance happiness, and innovative approaches to cultivating empathy in a disconnected world. Their conversation inspires listeners to embrace kindness as a powerful, transformative tool.

Dec 21, 2021 • 38min
How to Build Your Emotional Agility and Resilience – Susan David, Ph.D. & Joan Rosenberg, Ph.D. : 887
Join Susan David, an award-winning Harvard psychologist, and Joan Rosenberg, a master clinician, as they explore the art of emotional agility and resilience. They discuss how to navigate difficult emotions without resorting to positive thinking. Learn practical strategies for engaging with emotions compassionately, reclaiming your power, and enhancing relationships. The duo also shares insights on fostering emotional awareness in children, empowering both parents and kids to thrive in challenging situations.

Dec 17, 2021 • 10min
Mini-Episode: Cool Facts Friday #18
This installment dives into fascinating discoveries about ancient diets, featuring beer and blue cheese found in prehistoric feces. It highlights groundbreaking blood markers that can detect early signs of dementia. The concept of 'team flow' is explored, showcasing how collective brainwave patterns enhance teamwork. Trauma-focused therapy's effectiveness for PTSD is discussed, alongside promising research on using MDMA for trauma recovery. This mix of science and innovative treatments challenges conventional views on mental health.

Dec 16, 2021 • 1h 26min
Erectile Dysfunction: Causes, Solutions and Why It’s Normal – Dr. Paul Thompson : 886
In this enlightening discussion, Dr. Paul Thompson, a urologist and men's sexual health expert, addresses the common yet often stigmatized issue of erectile dysfunction. He emphasizes that ED can affect men of all ages and examines its causes, including hormones, nutrition, exercise, and mindset. The conversation explores innovative treatments like acoustic wave therapy and highlights the importance of holistic lifestyle adjustments. Dr. Thompson also connects oral health to cardiovascular wellness, revealing how systemic health impacts sexual function.

Dec 15, 2021 • 1h 10min
The Stress-Sleep Connection That’s Keeping You Up at Night – Dr. Dave Rabin : 885
Join Dr. Dave Rabin, a neuroscientist and health tech entrepreneur, as he dives into the intricate relationship between stress and sleep. Discover how chronic stress disrupts sleep and how tools like the Apollo device can help restore balance. Dr. Rabin shares insights on effective practices such as breathwork and meditation, emphasizing their significance for entrepreneurs facing unique challenges. He also highlights the healing power of vibrations and innovative technologies in enhancing well-being, demonstrating that managing stress is key to unlocking better sleep.

Dec 9, 2021 • 1h 18min
Hacking Longevity Starts with Detoxification – Chris Shade, Ph.D. : 884
Chris Shade, Ph.D., founder of Quicksilver Scientific, discusses detoxification's crucial role in longevity. He introduces a six-spoke 'longevity wheel' to illustrate how toxins and hormones impact aging. The conversation dives into the effectiveness of methods like coffee enemas and bile flow in liver health. Shade outlines a structured three-month detox plan aimed at enhancing cellular health and resilience. He also explores alternatives to hormone replacement for women and the significance of monitoring hormones to optimize well-being.

Dec 7, 2021 • 1h 17min
Toss the Candles! Biological Age Is Your New Birthday – Ryan Smith : 883
Ryan Smith, co-founder of TruDiagnostic and a biochemist, dives into the fascinating world of biological aging. He reveals how epigenetic methylation can determine your biological age compared to your chronological age. The discussion underscores the importance of understanding this distinction for health and longevity. They explore innovative blood tests for anti-aging insights, the role of machine learning in assessing biological age, and even the impacts of environmental factors like lead. Get ready to rethink your approach to aging!

Nov 30, 2021 • 54min
A Bacteria That Guards Your Gut Lining – Colleen Cutcliffe, Ph.D. : 881
Colleen Cutcliffe, Ph.D., founder of Pendulum Therapeutics, dives into the fascinating world of gut health. She explains how the gut lining acts as a protective barrier and introduces Akkermansia, a bacteria that enhances gut integrity and immune response. The conversation covers how dietary practices, like fasting and fiber intake, influence gut microbiome health. They also discuss the interplay between probiotics and prebiotics and reveal innovative research linking gut health to conditions like diabetes, making a strong case for prioritizing gut wellness.

Nov 26, 2021 • 12min
Mini-Episode: Cool Facts Friday #17
Discover how migraines can disrupt your deep and REM sleep, impacting overall well-being. Explore the fascinating ways your gut microbiome influences Type 2 diabetes, and learn about innovative biodegradable materials for male contraception. Uncover how specialized video games are helping kids manage their emotions effectively. Finally, challenge traditional sleep norms as studies reveal that around 6.5 hours of quality sleep may actually benefit your brain health.

Nov 23, 2021 • 35min
Alzheimer’s Targets Women’s Brains Decades Before Symptoms Show – Maria Shriver & Dr. Lisa Mosconi : 880
Maria Shriver, an award-winning journalist and advocate for Alzheimer’s awareness, joins Dr. Lisa Mosconi, a neuroscientist specializing in brain health. They delve into why Alzheimer’s disproportionately affects women, often revealing symptoms decades earlier than presumed. The duo discusses the critical links between hormonal changes, stress, and nutrition in preventing cognitive decline. They also emphasize innovative community efforts and proactive steps like mental stimulation and exercise for enhancing brain health, shedding light on essential strategies for awareness and prevention.