The Human Upgrade: Biohacking for Longevity & Performance

Toss the Candles! Biological Age Is Your New Birthday – Ryan Smith : 883

Dec 7, 2021

Ryan Smith, co-founder of TruDiagnostic and a biochemist, dives into the fascinating world of biological aging. He reveals how epigenetic methylation can determine your biological age compared to your chronological age. The discussion underscores the importance of understanding this distinction for health and longevity. They explore innovative blood tests for anti-aging insights, the role of machine learning in assessing biological age, and even the impacts of environmental factors like lead. Get ready to rethink your approach to aging!

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ANECDOTE

Founder's Age

Ryan Smith, despite being a founder of an aging diagnostics company, discovered his biological age was slightly older than his chronological age.
He improved it by 1.5 years in about a year, focusing on stress and sleep.

INSIGHT

Men vs. Women Aging

Men, on average, experience accelerated aging more often than women.
About 50% of men show signs of advanced aging, even in relatively healthy populations.

INSIGHT

Telomeres vs. Methylation

Telomere length, while extensively studied, isn't as predictive of health outcomes as epigenetic methylation.
Epigenetic clocks, measuring methylation, offer a more robust and predictive measure of biological age.

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IN THIS EPISODE OF THE HUMAN UPGRADE™…

…you’re going to discover how old you really are by taking a dive into the science of epigenetic methylation and biological aging. You’re going to find out about gene function, gene expression and what it has to do with how you age—and why it matters.

Biochemist Ryan Smith co-founded TruDiagnostic, a company focused on methylation array-based diagnostics for life extension and preventive healthcare. TruDiagnostic, a CLIA certified lab and health data company, developed the TRUAGE anti-aging test.

From a small blood test, TruDiagnostic can tell you your biological age—how old your body acts, based on how it’s functioning (as opposed to your chronological age, which is the number of years you’ve been on Earth).

Biological age is one of the most impactful pieces of data you can have about yourself. Age is the number one predictor of death, and your biological age matters more than the number of times you’ve been around the sun.

For example, you could be 42, and if you take great care of yourself, your biological age may be 30… Or, if you take poor care of yourself, your biological age may be 60.

Either way, TruDiagnostic will tell you how old you really are. And their test goes further than that. After you discover your biological age, TruDiagnostic also gives you a list of strategies to reverse aging based on your unique genetics. In other words, you get personalized anti-aging biohacks—and you can test your age over time to see if you’re getting younger, so you know whether or not your anti-aging hacks are working.

If you can turn back the clock on your biological age, you unlock the door to a longer, better life.

It feels like the cusp of a big change in longevity research with science and data now more fully supporting this work. TruDiagnostic currently has over 30 approved clinical research studies underway investigating how epigenetic methylation changes impact how long you live and how well you age.

In this episode, you’ll also learn:

Why men age worse than women, and what you can do about it
The best ways to predict your biological age (hint: grip strength is one of them)
How getting COVID changes the speed at which you age
Why small amounts of stress are amazing for anti-aging (and the right ways to stress your body and brain so you age in reverse)

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