The Primal Podcast Ep 125 - Dr Koutnik | The Longest HIGH FAT Study Ever Conducted Is Finally Finished (Surprising Results)
Jul 13, 2025
Dr. Andrew Koutnik, a metabolic scientist and type 1 diabetic, shares insights from his groundbreaking 10-year study on a high-fat ketogenic diet. He reveals surprising results regarding glycemic control and cardiovascular health in high-risk patients. The conversation explores the complex relationship between obesity and diabetes, challenges traditional views on caloric balance, and emphasizes the benefits of ketogenic diets. Koutnik advocates for prioritizing key health metrics over conventional concerns, providing a fresh perspective on diet and metabolic health.
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Complex Metabolic Dysfunction Revealed
- Metabolic diseases like obesity and diabetes involve complex changes beyond weight, including insulin dysregulation and fat distribution.
- Early metabolic dysfunction includes elevated insulin, reduced insulin sensitivity, increased visceral fat, and fatty liver disease.
Glucose Beats LDL for Heart Risk
- Glucose control outscores LDL cholesterol as a top cardiovascular risk in diabetes.
- HbA1c is a superior chronic risk marker compared to isolated blood glucose or LDL levels.
Ketogenic Diet for Glucose Control
- Lower dietary carbohydrates to reduce glucose and insulin levels to manage diabetes risks.
- A ketogenic diet with under 30 grams of carbs daily shifts fuel use toward fat and ketones, improving metabolic control.