This Podcast Will Kill You

Ep 9 Tuberculosis: A Slow Burn

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Jan 2, 2018
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ANECDOTE

Dickens' Description of Tuberculosis

  • Erin Omen Updike reads a dramatic passage describing a disease.
  • The passage is from Charles Dickens' 1879 novel, Nicholas Nickleby, and describes tuberculosis.
INSIGHT

Low Active TB Development Rate

  • Tuberculosis has a unique characteristic: even with infection, active TB develops in only 5-15% of cases.
  • This means most infected individuals carry the bacteria without experiencing the disease.
INSIGHT

Tuberculosis Infection Process

  • Mycobacterium tuberculosis enters the respiratory tract, evades initial immune responses, and reaches the alveoli.
  • It multiplies slowly, becomes encased by immune cells (latent stage), and reactivates when the immune system weakens.
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