

This Podcast Will Kill You
Exactly Right and iHeartPodcasts
This podcast might not actually kill you, but Erin Welsh and Erin Allmann Updyke cover so many things that can. In each episode, they tackle a different topic, teaching listeners about the biology, history, and epidemiology of a different disease or medical mystery. They do the scientific research, so you don’t have to.
Since 2017, Erin and Erin have explored chronic and infectious diseases, medications, poisons, viruses, bacteria and scientific discoveries. They’ve researched public health subjects including plague, Zika, COVID-19, lupus, asbestos, endometriosis and more.
Each episode is accompanied by a creative quarantini cocktail recipe and a non-alcoholic placeborita.
Erin Welsh, Ph.D. is a co-host of the This Podcast Will Kill You. She is a disease ecologist and epidemiologist and works full-time as a science communicator through her work on the podcast. Erin Allmann Updyke, MD, Ph.D. is a co-host of This Podcast Will Kill You. She’s an epidemiologist and disease ecologist currently in the final stretch of her family medicine residency program.
This Podcast Will Kill You is part of the Exactly Right podcast network that provides a platform for bold, creative voices to bring to life provocative, entertaining and relatable stories for audiences everywhere. The Exactly Right roster of podcasts covers a variety of topics including science, true crime, comedic interviews, news, pop culture and more. Podcasts on the network include My Favorite Murder with Karen Kilgariff and Georgia Hardstark, Buried Bones, That's Messed Up: An SVU Podcast and more.
Since 2017, Erin and Erin have explored chronic and infectious diseases, medications, poisons, viruses, bacteria and scientific discoveries. They’ve researched public health subjects including plague, Zika, COVID-19, lupus, asbestos, endometriosis and more.
Each episode is accompanied by a creative quarantini cocktail recipe and a non-alcoholic placeborita.
Erin Welsh, Ph.D. is a co-host of the This Podcast Will Kill You. She is a disease ecologist and epidemiologist and works full-time as a science communicator through her work on the podcast. Erin Allmann Updyke, MD, Ph.D. is a co-host of This Podcast Will Kill You. She’s an epidemiologist and disease ecologist currently in the final stretch of her family medicine residency program.
This Podcast Will Kill You is part of the Exactly Right podcast network that provides a platform for bold, creative voices to bring to life provocative, entertaining and relatable stories for audiences everywhere. The Exactly Right roster of podcasts covers a variety of topics including science, true crime, comedic interviews, news, pop culture and more. Podcasts on the network include My Favorite Murder with Karen Kilgariff and Georgia Hardstark, Buried Bones, That's Messed Up: An SVU Podcast and more.
Episodes
Mentioned books

Sep 16, 2025 • 48min
Special Episode: Mary Roach & Replaceable You
When your car breaks down or your fridge goes on the fritz, you can order a replacement part and get things back up and running in no time. The same cannot always be said for another intricate machine: the human body. For centuries, scientists have grappled with making or transplanting suitable replacements for nearly every body part, from hearts to hair and from legs to lungs. We’ve come quite a long way in that quest, so that at times, it feels as though we’re living in a sci-fi novel, where skin cells are printed and we can grow a customized heart. Yet we still have further to go, thanks to our magnificent immune system, who proves to be quite a worthy opponent. Here to tell you all about the weird and wonderful world of regenerative medicine is the one and only Mary Roach, who joins us this week to chat about her latest book Replaceable You: Adventures in Human Anatomy. As with any Mary Roach production, this is the perfect combination of informative, fascinating, and fun. Tune in today! Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.

Sep 9, 2025 • 1h 6min
Ep 187 Hypothermia Part 2: How it helps
Last week, we took you through all the ways that cold can harm us and the harrowing history of humans perishing at its icy hands. Ending the story there would be skipping over the parts where cold gets to play the hero, rather than the villain. In the second installment of this frosty miniseries, we explore the situations in which we might use cold to protect us and how it actually works. We also delve into the surprisingly long (and unsurprisingly grim) history of therapeutic hypothermia, a journey that wouldn’t be complete without a debate over sea cloaks, a reconsideration of the plot of Titanic, and a brief jaunt into cryonics. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.

Sep 2, 2025 • 58min
Ep 186 Hypothermia Part 1: How it hurts
For all our wondrous adaptations as a species - our big brains, our capacity for language, our opposable thumbs - we humans are not well-equipped to deal with the cold. Take us out of our insulated dwellings, take away our winter clothes, and things can get dicey fast. From frostbite to hypothermia, the cold can settle into our bones, leading us down a path where injury or death are possible outcomes. In this episode, we explore that path: how our meager cold-survival adaptations are vastly outshone by other animal species, the long and grim history of hypothermia in war, and what exactly is happening inside your body when your temperature drops. Tune in to this unexpectedly strange grab-bag of an episode. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.

20 snips
Aug 26, 2025 • 52min
Special Episode: Lina Zeldovich & The Living Medicine
Lina Zeldovich, a journalist and author of *The Living Medicine*, sheds light on phage therapy, an innovative treatment for antibiotic-resistant infections. She discusses the rise of antimicrobial resistance and how this forgotten cure, used since before antibiotics, is making a comeback. The conversation dives into the fascinating history of phage therapy, including its development during World War II and the political challenges it faced. Zeldovich advocates for this solution as a vital alternative to combat the growing healthcare crisis.

Aug 19, 2025 • 1h 14min
Ep 185 The Great Smog of London: “Thick, drab, yellow, disgusting”
Some things just go together: peanut butter and jelly, bacon and eggs, milk and cereal, London and smog. Or at least, that’s the way things used to be until the Great Smog of 1952. (Don’t worry, the first three pairings are safe). If you’ve watched The Crown, you may remember an early episode in which a thick, noxious smog surrounded the entire city of London for days on end. People coughing, hacking, collapsing. Traffic ground to a standstill. Authorities in denial. What was actually going on in December 1952 to lead to such conditions? What was in the smog to make it so toxic? And how did this severe pollution event lead to massive changes in air quality regulations around the world? Tune in to find out all this and more (including what The Crown got wrong). Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAuSee omnystudio.com/listener for privacy information.

Aug 12, 2025 • 1h 23min
Ep 184 The Gallbladder: Humor us
Discover the often-overlooked gallbladder and its dramatic role in digestive health. The hosts share humorous personal stories about gallbladder pain, including a harrowing journey to diagnosis. Dive into the fascinating world of bile — its history, functions, and quirky characteristics. Learn about gallstone formation, the health implications, and life after gallbladder removal. The light-hearted banter keeps the mood lively while exploring the gallbladder's historical ties to ancient medical theories and personal temperament.

Aug 5, 2025 • 49min
Special Episode: Carl Zimmer & Airborne
Carl Zimmer, an award-winning science writer and author of 'Airborne: The Hidden History of the Life We Breathe,' joins the discussion to reveal the fascinating world of aerobiology. He highlights the critical distinction between airborne and droplet transmission, especially during the COVID pandemic. The conversation dives into historical misconceptions about disease spread, featuring pioneers like Fred Meyer, whose remarkable research changed our understanding of airborne pathogens. Listeners will learn about the unseen life in our atmosphere and its implications for public health.

21 snips
Jul 29, 2025 • 1h 10min
Ep 183 SSRIs Part 2: Action
Dive deep into the fascinating world of SSRIs and discover how they interact with serotonin. Hear personal journeys of individuals reclaiming their lives from anxiety and OCD through these medications. Explore the historical context and the complicated discourse surrounding SSRIs and their effectiveness. Unpack the nuances of serotonin syndrome and the importance of personalized treatment approaches. Plus, enjoy some humorous metaphors making neuroscience a little more engaging!

8 snips
Jul 22, 2025 • 1h 2min
Ep 182 SSRIs Part 1: Origin
The fascinating origins of SSRIs reveal a journey through millions of years and the animal kingdom. The podcast examines how societal factors shaped the rise of these antidepressants, blending personal anecdotes with historical context. It explores the complex relationship between serotonin and mental health, including stigma and the evolving understanding of depression treatment. Intriguingly, it touches on the surprising link from tuberculosis to Prozac, highlighting the scientific evolution and controversies that surround these medications.

Jul 15, 2025 • 56min
Special Episode: Wendy Chin-Tanner & King of the Armadillos
Wendy Chin-Tanner, author and sociologist, shares insights from her novel, King of the Armadillos, which draws from her father's experiences with Hansen's disease. The discussion touches on the stigma of leprosy, the vibrant community formed in Carville, and how personal histories shape narratives. Wendy highlights the complexities of illness, advocacy, and resilience against societal fears, weaving a heartfelt tale of connection and memory through her creative process. Tune in for an inspiring journey through forgotten public health history.