FoundMyFitness

Dr. Rhonda Patrick dives deep into the fascinating world of vitamin C. Discover its role in boosting immunity, especially in fighting the common cold and improving lung function. There's a discussion on oral versus intravenous administration and its effects on cancer therapy. Learn how it ties into exercise adaptation and even fatty acid oxidation. Safety concerns are addressed too, plus intriguing insights into vitamin C's impact on brain health and fertility. This is a treasure trove of information about a vitamin that influences so much more than we realized!

Dr. Rhonda Patrick answers pressing COVID-19 questions, addressing how the virus affects children and its transmission. The discussion dives into potential treatments, including hydroxychloroquine and quercetin as zinc ionophores. Blood type's influence on susceptibility is explored, with intriguing insights on the protective nature of type O. Vitamin D's impact on health and COVID-19 risk is analyzed, alongside the potential benefits of sauna use and high-dose intravenous vitamin C. Melatonin's role in inflammation and virus severity is also examined.

In this engaging discussion, Kevin Rose, a tech entrepreneur and health enthusiast, dives into cutting-edge research on brain health and nutrition. He examines how phospholipid DHA boosts cognitive function and the longevity effects of metformin. The benefits of sulforaphane from cruciferous vegetables and its impact on brain health are highlighted. They also explore magnesium threonate for cognitive enhancement and how sauna use can mimic the effects of exercise, improving overall wellness. Intriguing insights for health aficionados!

Dive into the fascinating world of resveratrol and its potential as a longevity compound. Discover how this plant-derived substance can improve cardiovascular biomarkers and offer anti-inflammatory benefits. Learn about the surprising effects on cognition and memory, as well as its role in extending healthspan in animals. The discussion reveals the complex interplay of resveratrol with exercise and its effects on drug metabolism. Find out what factors influence its bioavailability and the implications for supplementation.

Discover the crucial role of NAD+ in the aging process and how its levels decline over time. Learn about the promising precursors, nicotinamide riboside and nicotinamide mononucleotide, and their potential to boost NAD+. The discussion also tackles whether NAD+ boosters can promote cancer growth and explores why direct supplementation of NAD+ might not be effective. Tune in for insights from current research and clinical trials that could reshape our understanding of longevity and cellular health.

Dr. David Sinclair, a Harvard genetics professor and aging researcher, shares fascinating insights into the mechanisms of aging and how to potentially slow it down. He reveals how caloric restriction, fasting, and compounds like resveratrol can activate longevity genes. The discussion also covers the role of NAD+ in reversing aging processes and the exciting potential of reprogramming adult cells into stem cells. Listeners will learn about promising advancements in cognitive health, particularly in relation to Alzheimer's, and how NMN and NR might improve brain function.

Discover how sauna use might mimic the benefits of exercise for heart health and longevity. Clinical research reveals significant improvements in cardiovascular well-being through regular sauna bathing. The comparison between Finnish sauna and Waon infrared therapy unveils intriguing differences. Heat shock proteins play a crucial role in mediating the health benefits, while sauna use is shown to reduce inflammation. Plus, it's an enjoyable and safe practice anyone can consider integrating into their routine!

Discover the science behind exercise as a powerful antidote to depression. Learn how physical activity boosts serotonin, enhances neuroplasticity, and increases endorphins. Explore the intricate link between inflammation and mental health, revealing how exercise helps reduce harmful compounds. Delve into the dual role of IL-6 during workouts and its impact on mood. This insightful discussion unpacks various exercise types and their specific benefits, making a compelling case for incorporating movement into mental health management.

Dr. Elissa Epel, a leading professor at UCSF, dives into the fascinating world of telomeres and their critical role in aging. She discusses how stress, nutrition, and lifestyle factors, like exercise and meditation, can influence telomere length and overall health. Epel highlights the damaging effects of sugar and stress on our biological age, while emphasizing the importance of maintaining a healthy lifestyle to promote longevity. Discover the intricate connections between our choices, cellular health, and the quest for a better quality of life as we age.

Matthew Walker Matthew Walker, Ph.D., is a professor of neuroscience and psychology at the University of California, Berkeley, and serves as the Director of the Center for Human Sleep Science.  Walker's research examines the impact of sleep on human health and disease. One area of interest focuses on identifying "vulnerability windows" during a person's life that make them more susceptible to amyloid-beta deposition from loss of slow wave sleep and, subsequently, Alzheimer's disease later in life. Dr. Walker earned his undergraduate degree in neuroscience from the University of Nottingham, UK, and his Ph.D. in neurophysiology from the Medical Research Council, London, UK. He is the author of the New York Times best-selling book Why We Sleep: Unlocking the Power of Sleep and Dreams. In this episode, we discuss: (00:00) Introduction (08:47) Sleep boosts learning (21:21) Manipulating sleep to enhance learning (26:28) REM sleep, dreams, and memory encoding (34:46) Sleep deprivation causes loneliness (46:36) Sleep is disturbed in all neuropsychiatric conditions (52:30) Bright light exposure  (01:00:02) How much sleep is enough? (01:10:21) Inflammation triggers sleep (01:26:16) Bidirectional relationship between poor sleep and Alzheimer's disease (01:35:12) Deep sleep deprivation increases beta-amyloid (01:41:40) Preventing dementia (01:48:44) Sleep tracking technology (01:56:25) Four Pillars of Sleep (02:06:02) Metabolism and microbiome (02:23:34) Tips for better sleep If you’re interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information on sleep for enhanced learning straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor