FoundMyFitness #052 New Omega-3, sulforaphane research, and more! [Kevin Rose Show]
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Jan 6, 2020 
In this engaging discussion, Kevin Rose, a tech entrepreneur and health enthusiast, dives into cutting-edge research on brain health and nutrition. He examines how phospholipid DHA boosts cognitive function and the longevity effects of metformin. The benefits of sulforaphane from cruciferous vegetables and its impact on brain health are highlighted. They also explore magnesium threonate for cognitive enhancement and how sauna use can mimic the effects of exercise, improving overall wellness. Intriguing insights for health aficionados!
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Omega-3 DHA and Brain Health
- Rhonda Patrick emphasizes the importance of DHA, an omega-3, for brain health, especially its transport across the blood-brain barrier.
- Two forms of DHA bind to albumin, one using passive diffusion, hindered by aging and APOE4, and the other using active transport via MFSD2A.
APOE4 and Alzheimer's Risk
- The APOE4 gene significantly increases Alzheimer's risk: twofold with one copy and ten to fifteenfold with two copies.
- A staggering 65–85% of Alzheimer's patients possess at least one copy of the APOE4 allele.
Optimizing DHA Intake
- Prioritize phospholipid DHA from sources like fish roe (38-75% phospholipid DHA) for better brain uptake.
- Supplement with high-quality triglyceride form fish oil and consume fish alongside roe for optimal intake.