FoundMyFitness #050 NAD+ in Aging: Role of Nicotinamide Riboside and Nicotinamide Mononucleotide
Nov 13, 2019
Discover the crucial role of NAD+ in the aging process and how its levels decline over time. Learn about the promising precursors, nicotinamide riboside and nicotinamide mononucleotide, and their potential to boost NAD+. The discussion also tackles whether NAD+ boosters can promote cancer growth and explores why direct supplementation of NAD+ might not be effective. Tune in for insights from current research and clinical trials that could reshape our understanding of longevity and cellular health.
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NAD+ and Aging
- NAD+ is crucial for life and declines with age, impacting many hallmarks of aging.
- NAD+ boosters like NR and NMN may improve tissue aging in animals, showing promise in human trials.
NAD+'s Role
- NAD+ is essential for DNA repair and energy production, both declining with age.
- It activates sirtuins, enzymes linked to longevity, influencing metabolic processes.
NAD+ Sources
- The body synthesizes NAD+ from dietary sources like tryptophan and niacin (vitamin B3).
- However, dietary NAD+ isn't the major source; recycling is, due to high bodily demand.