

The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life.
Episodes
Mentioned books

133 snips
Dec 28, 2023 • 59min
Urolithin A: The Miracle Compound - Dr. Dominic Denk : 1119
In this conversation, Dr. Dominic Denk, a physician specializing in aging and cancer research at University Hospital Frankfurt, illuminates the groundbreaking benefits of Urolithin A. Find out how this powerful compound supports mitochondrial health, boosts muscle strength, and enhances cognitive function. Dr. Denk dives into its role in cancer prevention and autoimmunity while discussing the differences in healthcare approaches between the U.S. and Germany. Uncover the potential of Urolithin A to revolutionize your wellness routine and longevity.

31 snips
Dec 26, 2023 • 1h 8min
How & Why You Age, And What It Takes To Be 'Young Forever' – Mark Hyman, M.D. - End of Year Best-Of Episode! : 1118
Mark Hyman, M.D., a functional medicine expert and author of "Young Forever," joins the discussion on the science and secrets of aging. He shares the Top 10 hallmarks of aging and the crucial role of inflammation in aging, introducing terms like "Inflammaging." Discover how dietary choices, metabolic flexibility, and lifestyle changes can reverse biological age—Hyman effectively reduced his own by 20 years! They also explore innovative approaches like hyperbaric chambers and practical strategies to enhance healthspan and longevity.

28 snips
Dec 21, 2023 • 1h 14min
Change Absolutely Everything With One Hack – Robert Waldinger, M.D. - End of Year Best-Of Episode! : 1117
Robert Waldinger, M.D., a Harvard psychiatrist and leader of the Harvard Study of Adult Development, shares insights from an 80-year research project on happiness. He reveals that strong, quality relationships are essential for long-term health and well-being. Listeners learn about the importance of social fitness, how relationships can combat loneliness, and the surprising value of casual connections. Waldinger also discusses attachment styles and offers practical tools to enhance relationships, making a compelling case for nurturing our social ties.

Dec 19, 2023 • 1h 4min
The Equinox Effect: Innovating Fitness – Lavinia Errico : 1116
Lavinia Errico, co-founder of Equinox Fitness Clubs and founder of MoveJoy, discusses her transformative journey in the fitness industry. She reflects on the challenges of launching Equinox in 1980s NYC, emphasizing the importance of community and aesthetics in creating joyful workout experiences. Lavinia also shares insights on balancing entrepreneurship with motherhood and the evolving focus on mental wellness over traditional fitness goals. Her initiative, MoveJoy, aims to make workouts more stress-free and inclusive for everyone.

39 snips
Dec 14, 2023 • 1h 27min
Reversing Age: The Quest for Immortality with Bryan Johnson : 1115
In a captivating discussion, Bryan Johnson, an entrepreneur and rejuvenation athlete, dives into the intersection of neuroscience and longevity. He highlights his groundbreaking brain-monitoring technology at Kernel and shares insights on how loneliness can impact lifespan. The conversation veers into the controversial topic of testosterone's role in health. Bryan also explores the consequences of criticism on well-being and muses about preferred respect from future generations. Expect surprising takes on diet, relationships, and the future of human evolution!

40 snips
Dec 12, 2023 • 1h 12min
From Michelin Stars to Mental Clarity: The Nootropic Revolution - Dan Freed : 1114
In this engaging discussion, Dan Freed, Founder and CEO of Thesis Nootropics, shares his fascinating journey from Michelin-starred chef to cognitive enhancement pioneer. He opens up about battling burnout and ADHD, discovering the transformative power of nootropics. Tune in as they delve into personalized nootropic solutions, the importance of quality and regulation in the supplement industry, and innovative approaches to managing neurochemistry. Dan also highlights the vital role of focus in unlocking our brain's potential.

4 snips
Dec 7, 2023 • 1h 6min
How Intermittent Fasting Works for Women! – Cynthia Thurlow, NP
Cynthia Thurlow, a Johns Hopkins-trained nurse practitioner and functional nutritionist, shares her expertise on intermittent fasting specifically for women. She discusses how hormonal changes throughout the menstrual cycle impact fasting strategies, emphasizing personalized approaches for different life stages, including menopause. Cynthia debunks diet dogma and stresses the importance of lifestyle factors like sleep and stress management. She highlights tailored fasting techniques and explores how epigenetic factors influence reproductive health and nutrition.

6 snips
Dec 5, 2023 • 1h 24min
Beyond the Bedroom: Hacking Your Erotic Blueprint - Miss Jaiya : 1112
Miss Jaiya, an award-winning somatic sexologist and creator of The Erotic Blueprints® Framework, dives into the fascinating world of erotic blueprints. She discusses the four fundamental drives of human biology—fear, food, friends, and fertility—while emphasizing sexuality's vital role in well-being. Jaiya explores how understanding personal erotic blueprints can empower individuals, enhance intimacy, and even influence creativity. Listeners are encouraged to embrace their desires and break societal taboos for richer, more fulfilling relationships.

39 snips
Nov 30, 2023 • 1h 11min
Build A Better Brain: Strategies for Strengthening Cognitive Function – Jim Kwik : 1111
Jim Kwik, a renowned memory and cognitive function expert, shares his transformative journey from overcoming a childhood brain injury to mastering mental enhancement techniques. He discusses the power of nootropics for brain health, daily biohacking strategies, and the intriguing concept of identifying cognitive styles through animal archetypes. With humor and personal stories, Jim emphasizes the importance of mindset in improving memory and productivity, while offering practical tips to unleash one's true genius.

5 snips
Nov 28, 2023 • 1h 9min
Making Billions: Lessons Learned From the King of the Thrill Pill Cult – Shaahin Cheyene : 1110
Shaahin Cheyene is a captivating entrepreneur known for creating a billion-dollar herbal ecstasy business in the '90s. He shares his incredible journey from fleeing Iran to living in his car before hitting it big in the supplement industry. Cheyene sheds light on the challenges of navigating government regulations and his evolution into an Amazon expert. He also discusses the potent history of ephedra, the importance of mentorship, and how self-defense skills complement a thriving entrepreneurial mindset. Prepare for an entertaining ride filled with daring ventures and insightful lessons!