FoundMyFitness

#041 Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia

Mar 19, 2018

01:58:42

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Episode guests

Charles Raison

Highlights

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Episode notes

Thermoregulation - The Greatest Thermostat in the Animal World

01:46

Bipolar Disorder Is Response to the Adversity of Time, Right?

02:35

Hypothermia

03:22

Introduction

4min

The Found My Fitness Podcast

2min

The Importance of Inflammation in Depression

4min

Depressed People Are More Likely to Kill Theirself Than Sick People

4min

The Link Between Inflammation and Depression

2min

Is There a Depression Risk Factor?

1min

The Risk Factor of Depression in Africa

5min

Is There a Relationship Between Inflammation and Depression?

2min

Is There Any Evidence That Endotoxin Causes Depression?

2min

10.

The Endotoxin, the LPS, and the Typhoid Stimulus

2min

11.

CNS Inflammation

5min

12.

The Postprandial Inflammatory Response

4min

13.

Hyperthermia

3min

14.

How Does the Sauna Help Autistic Symptoms?

6min

15.

Hypothermia

3min

16.

Is Inflammation Depressogenic?

3min

17.

The Anti-Inflammatory Effects of Exercise

2min

18.

Thermoregulation in Schizophrenics

2min

19.

Does Chronic Inflammation Delivered by Interferon Alpha Change Serotonin Metabolism?

4min

20.

Is Exercise a Cause of Depression?

2min

21.

Is the Heat Shock Protein 105 Driving Secondary Immune Effects?

2min

22.

Is There a Treatment for Depression?

2min

23.

The Importance of the Gut Microbiome in the Modern World

4min

24.

Running to the Point of Exhaustion

2min

25.

Thermoregulation - The Greatest Thermostat in the Animal World

2min

26.

What Are Psychedelics?

5min

27.

Why Should Inflammation Make You Ruminate?

4min

28.

Are You a Long-Term Meditator?

3min

29.

Do Antidepressants Really Work?

5min

30.

Antidepressants and the Chakra Room

3min

31.

The Ultimate Antidepressant Strategy

5min

32.

Is There a Link Between Light Exposure and Depression?

3min

33.

How Does the Light Around Your House Help With Depression?

3min

34.

Is the Moon in Madness Really a Light Source?

3min

35.

Bipolar Disorder Is Response to the Adversity of Time, Right?

3min

36.

Bipolar Disorder

2min

37.

The New Mind Body Science of Depression by Chuck Rason

3min

Charles Raison

Charles Raison, M.D. is a professor at the School of Human Ecology at the University of Wisconsin-Madison and Founding Director of the Center for Compassion Studies in the College of Social and Behavioral Sciences at the University of Arizona.

Dr. Raison’s research focuses on inflammation and the development of depression in response to illness and stress. He also examines the physical and behavioral effects of compassion training on the brain, inflammatory processes, and behavior as well as the effect of heat stress as a potentially therapeutic intervention major depressive disorder.

In this episode, you'll discover:

(00:00) Introduction
(06:26) Role of inflammation in depression
(10:08) Evolutionary mechanism
(16:19) Genetics of depression
(22:57) How obesity causes depression biochemically
(33:32) Does exercise treat depression
(36:08) Hyperthermia as treatment
(46:08) Inflammation promotes depression
(53:39) Did we evolve to need hormetic stress?
(01:03:38) Heat-shock proteins
(01:06:10) Repurposing ancient wisdom
(01:17:31) Psychedelics and meditation
(01:27:51) What is the role of conventional pharmacotherapy?
(01:35:19) Lifestyle modifications for depression
(01:42:21) Why light and circadian rhythm are important for mental health

If you’re interested in learning more, you can read the full show notes here.

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