#041 Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia
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The Risk Factor of Depression in Africa
There is an argument that depression might be something of a more modern phenomenon arising from this sort of evolutionary mismatch between the way we live now and how we evolved to live. And there's evidence that rates of depression have really kind of risen a great deal in many parts of the modern world in the last 50 years at exactly the times when our diets become more pro-inflammatory, where we've been separated from a lot of immunoregulatory organisms in the environment. But if that's the story, then you would not expect to see depression being ancient for one thing, but especially you wouldn't expect to see any type of link between inflammatory activation and depression with people that are not living in a
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