The Tim Ferriss Show #237: Exploring Smart Drugs, Fasting, and Fat Loss -- Dr. Rhonda Patrick
Sulforaphane Benefits
- Sulforaphane, found in broccoli sprouts, activates the Nrf2 pathway, boosting cellular resilience.
- This compound acts as a xenohormetic, a mild stressor that triggers beneficial stress responses.
Time-Restricted Eating Best Practices
- Practice time-restricted eating (TRE) within a 9-12 hour window, ideally aligning with your circadian rhythm.
- Start with a 10-hour window and consider stricter 8-9 hour windows for potential endurance benefits.
Fasting vs. Keto
- Prolonged fasting (4-5 days) triggers autophagy and apoptosis, clearing damaged cells, unlike keto.
- Fasting increases stem cell production, improves cellular repair, and boosts NAD+ levels.
Rhonda Patrick, PhD, (@foundmyfitness) is an American biochemist and scientist. She first appeared on this podcast back in episode twelve, and whether you want to extend life, inexpensively buy a stem cell "insurance policy," or guard against cancer, Rhonda has valuable insights and recommendations. In this episode, Rhonda tackles some of your most requested topics, including: Best practices for fasting (and who struggles most with time-restricted feedings) What blood tests are most important to analyze for overall health The "minimum effective dose" for the benefits of sauna Heat vs. cold exposure, and how they should be used effectively Most effective smart drugs The latest fat loss research And much, much more Rhonda is known for her studies of the mechanistic link between vitamin D and serotonin production, research that may have important implications for the understanding of autism and other disorders, and for her popular podcast, Found My Fitness. Dr. Patrick also conducts clinical trials, performed aging research at Salk Institute for Biological Studies, and did graduate research at St. Jude Children's Research Hospital, where she focused on cancer, mitochondrial metabolism, and apoptosis. Enjoy! This podcast is sponsored by Alibaba and Gateway17. If you're an entrepreneur or business owner in the US, the stars don't always align -- but this might get close. Alibaba (if you're not familiar with it, imagine Amazon and Google having a baby in China) is hosting Gateway17, a conference designed to help US businesses tap into the five hundred million consumers of China's growing middle class. Gateway17 takes place June 20-21 in Detroit, Michigan, and it puts you in direct contact with experts who want to help you grow your business into the booming Chinese marketplace. Speakers include Alibaba founder Jack Ma (in his only speaking engagement of the year), UPS CEO David Abney, and master interviewer Charlie Rose. As a Tim Ferriss Show listener, Alibaba is offering you a ticket for $125 (they're usually $500) if you sign up at gateway17.com by May 25 and use the code Tim at checkout. This podcast is also brought to you by WordPress, my go-to platform for 24/7-supported, zero downtime blogging, writing online, creating websites, and basically everything online. I love it to bits, and the lead developer, Matt Mullenweg, has appeared on this podcast many times. Whether for personal use or business, you're in good company with WordPress being used by The New Yorker, Jay Z, FiveThirtyEight, TechCrunch, TED, CNN, and Time, just to name a few. A source at Google told me that WordPress offers "the best out-of-the-box SEO imaginable," which is probably why it runs nearly 30 percent of the Internet. Go to WordPress.com/Tim to get 15% off your website today! Show notes and links for this episode can be found at www.fourhourworkweek.com/podcast.
***
If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to convince hard-to-get guests. I also love reading the reviews!
For show notes and past guests, please visit tim.blog/podcast.
Sign up for Tim’s email newsletter (“5-Bullet Friday”) at tim.blog/friday.
For transcripts of episodes, go to tim.blog/transcripts.
Interested in sponsoring the podcast? Visit tim.blog/sponsor and fill out the form.
Discover Tim’s books: tim.blog/books.
Follow Tim:
Twitter: twitter.com/tferriss
Instagram: instagram.com/timferriss
Facebook: facebook.com/timferriss
YouTube: youtube.com/timferriss
Past guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, and many more.
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.