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#237: Exploring Smart Drugs, Fasting, and Fat Loss -- Dr. Rhonda Patrick

The Tim Ferriss Show

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The Importance of Circadian Rhythm

In humans, metabolic genes are more active during the day and less active at night. The underlying reason for this is because humans are diurnal creatures - we conduct most of our activities during the day. We also have food influencing what are known as peripheral oscillators that occur in peripheral tissues such as the liver and influence metabolism. This helps to explain why time restricted eating begins with the first bite or drink of anything non water. Even compounds that exist in black coffee, such as caffine, can be reasonably expected produce metabolic effects including activity in the liver.

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