The Human Upgrade: Biohacking for Longevity & Performance What the Godfather of IF Eats - Mark Mattson, Ph.D. : 634
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Oct 10, 2019 
Mark Mattson, a leading neuroscience professor at Johns Hopkins University and intermittent fasting expert, dives deep into the brain benefits of fasting. He discusses how fasting enhances cognitive function and metabolic health, revealing it can even reverse diabetes and obesity. Mark shares practical fasting tips, including optimal eating times and dietary strategies for maximum brain performance. The conversation also touches on the roles of key growth factors like NGF and BDNF in brain health, making for an enlightening and health-focused dialogue.
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Intermittent Fasting Methods
- Try intermittent fasting by eating your daily calories within a smaller window.
- Explore various fasting methods, like 12-hour, 16-hour, or alternate-day fasting.
Calorie Restriction vs. Fasting
- Calorie restriction alone doesn't ensure a fasted state, as frequent meals replenish liver glycogen.
- True fasting involves depleting glycogen stores, mobilizing fats, and elevating ketone levels.
Exercise Timing
- Exercise before eating, ideally midday or early afternoon, after an overnight fast.
- This amplifies the benefits of both fasting and exercise, enhancing the ketogenic state and activating key pathways.
