Good Life Project Why Your Brain is Begging You to Take a Break (and How to Do It Right) | Dr. Mithu Storoni
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May 8, 2025 
Dr. Mithu Storoni, a neuroscience researcher and ophthalmic surgeon, dives into the pressing need for a work culture shift. She critiques the outdated industrial-age work model that contributes to stress and burnout. Mithu shares insights on aligning work with natural cognitive rhythms to unlock creativity and motivation. Discussion points include the evolution of work-related stress, the impact of AI on productivity, and the importance of intrinsic motivation. Finally, she emphasizes taking breaks to enhance well-being and fosters a harmonious relationship with one's values.
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9-to-5 Fails Knowledge Work
- The 9-to-5 work structure suits muscle-based labor but fails mind-based work demands.
- Knowledge work needs a different system emphasizing quality over quantity to reduce mental exhaustion.
Brain Efficiency Decays Rapidly
- Our brain grows less efficient when we sustain intense work beyond short periods.
- This efficiency decay makes effort feel harder and diminishes work quality over time.
Startup Mental Fuel Anecdote
- Startup founders endure grueling phases driven by personal vision and uncertainty tolerance.
- Intrinsic motivation fuels their prolonged mental energy through shifting brain states and rhythms.
