Bounce! Conversations with Larry Weeks

EP. 58: YOUR BRAIN ON DEPRESSION: DR. JOHN KRYSTAL ON ANTIDEPRESSANTS, PSYCHEDELICS, AND KETAMINE THERAPY

Nov 17, 2022
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Episode notes
1
Introduction
00:00 • 6min
2
What Happens in a Depressed Brain?
05:54 • 2min
3
Depression and GABA in the Brain
08:17 • 4min
4
The Biology of Depression
12:06 • 2min
5
Is There a Biochemical Change in the Brain?
14:30 • 5min
6
Sleep Deprivation and Depression
19:56 • 2min
7
Antidepressant Medications - Are They Effective?
22:06 • 6min
8
Is There a Subgroup of Patients Who Are Better Off on SSRIs or SNRIs?
27:50 • 3min
9
Anxiety and Depression - Are They Related?
30:56 • 5min
10
How Does Ketamine Work as an Anti-Depressant?
35:34 • 6min
11
The Subjective Effects of Ketamine Versus the Psychedelics
41:11 • 2min
12
The Antidepressant Response to Ketamine
42:53 • 2min
13
Antidepressant Effects of Ketamine
44:25 • 2min
14
Treatment Resistant Depression
46:22 • 2min
15
The Effects of Ketamine on Depression
47:53 • 4min
16
Is There a Difference Between the Intranasal and the Intravenous?
51:31 • 2min
17
K-Hole Experience - Is There Too Much?
53:56 • 2min
18
Side Effects and Risks of Ketamine in the Clinic
56:07 • 2min
19
Is There a Need for Access to Treatments Like Ketamine?
57:52 • 2min
20
Dr. Crystal, I'm Not a Theist, but You're Doing God's Work
59:56 • 2min