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EP. 58: YOUR BRAIN ON DEPRESSION: DR. JOHN KRYSTAL ON ANTIDEPRESSANTS, PSYCHEDELICS, AND KETAMINE THERAPY

Bounce! Conversations with Larry Weeks

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Is There a Subgroup of Patients Who Are Better Off on SSRIs or SNRIs?

There's a subgroup of patients who get these medications who might be better treated with other classes of medications. The goal is to get people to an adequate clinical response, which is more like a 50% reduction in depression. But it's really important for the treatment team not to give up just because the first treatment didn't produce an optimal response.

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