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EP. 58: YOUR BRAIN ON DEPRESSION: DR. JOHN KRYSTAL ON ANTIDEPRESSANTS, PSYCHEDELICS, AND KETAMINE THERAPY

Bounce! Conversations with Larry Weeks

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Treatment Resistant Depression

There are some people who seem to do very well with very few doses of ketamine. For reasons that we don't yet understand, we don't know if it's different patients or differences in how the drugs affects the brain. In more straightforward depression populations, they tend to get longer lasting antidepressant effects. It would be interesting to know what happens when these drugs are administered to patients with treatment resistant forms of depression and have greater risk of relapse.

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