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Inside Exercise

#80 - Epigenetics of exercise adaptation and "muscle memory" with Dr Kevin Murach

Feb 14, 2024
Dr Kevin Murach, an expert on muscle growth and adaptation to exercise training, discusses the concept of muscle memory and its relationship with epigenetics. The podcast explores studies on mice models, exploring endurance and strength effects, as well as the mechanisms of muscle memory such as epigenetics and microRNA. The importance of nuclei in muscle fibers for muscle growth and adaptation is also discussed.
01:41:53

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Muscle memory is a phenomenon where muscles adapt faster when retrained after a period of detraining, suggesting long-term changes happening at the cellular level.
  • The use of a progressive weighted wheel running model in mouse studies allows for the investigation of muscle memory and the effects of training, detraining, and retraining.

Deep dives

The podcast episode discusses the concept of muscle memory.

The podcast delves into the concept of muscle memory and its implications for exercise training. Muscle memory refers to the phenomenon where muscles adapt faster when retrained after a period of detraining. It is suggested that there are long-term changes happening at the cellular level in the muscle fibers themselves. The evidence for muscle memory is explored and the podcast discusses how it may be regulated, including factors like genetics, epigenetics, and changes in gene expression within the muscles.

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