The Rich Roll Podcast The Human Brain: Leading Experts On Preventing Cognitive Decline, Understanding Addiction, The Neurochemistry of Spirituality & The Mind-Body Connection
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Aug 28, 2025 
Andrew Huberman, a neuroscientist at Stanford, joins forces with Dean Sherzai, an expert on Alzheimer's prevention, psychiatrist Anna Lembke, spirituality pioneer Lisa Miller, and hypnosis researcher David Spiegel. They dive into how lifestyle choices can prevent cognitive decline and unravel the complexity of addiction, driven by dopamine. The discussion spans the interplay of spirituality and mental health, along with how hypnosis can heal. These insights reveal the brain's incredible adaptability and underscore the profound connection between mind, body, and spirit.
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Brain As Integrated Orchestrator
- The nervous system orchestrates sensation, perception, emotion, thought, and behavior as a single integrated system.
- Its job is to merge external perceptions with internal interoception to guide appropriate action in the world.
Focus Plus Rest To Rewire Your Brain
- Trigger neuroplasticity by combining intense focused attention with later periods of deep rest or sleep.
- Create urgency and concentrated practice to mark synapses for change, then consolidate during sleep.
Cognitive Decline Starts Decades Earlier
- Cognitive decline often begins decades before diagnosis and can be seen in people in their 50s and 60s.
- Early, continuous decline steals presence and 'us-ness' long before Alzheimer's is clinically labeled.
