This Podcast Will Kill You

Ep 48 Botulism: Why are you the way you are?

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Apr 14, 2020
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ANECDOTE

Georgia Hardstark's Botox Experience

  • Georgia Hardstark, co-host of My Favorite Murder, was initially hesitant about Botox.
  • Seeing its effect on a friend, looking "awake" and not necessarily younger, changed her perspective.
INSIGHT

C. botulinum Characteristics

  • Botulism is caused by Clostridium botulinum, a gram-positive, spore-forming, anaerobic bacterium.
  • Spores allow the bacteria to survive harsh conditions, including oxygen, which is important as C. botulinum cannot grow in its presence.
INSIGHT

Botulinum Toxin's Mechanism

  • Botulism isn't caused by the bacteria itself, but by botulinum toxin, a neurotoxin the bacteria produces.
  • This toxin blocks acetylcholine release, leading to flaccid paralysis because muscles don't receive contraction signals.
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