

The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes
Mentioned books

8 snips
Oct 18, 2023 • 1h 51min
How I Took 9 Years off My Age: Live From Toronto with Gene Therapy Pioneer Dr. Adeel Khan : 1098
Dr. Adeel Khan, a pioneer in gene and cell therapies, shares insights from his extensive work in regenerative medicine. He discusses his recent gene therapy experience, which promises to reduce biological age significantly. The conversation explores the evolution and impact of gene therapy on longevity, challenges in medical education, and the intersection of fitness and regenerative health. Khan also addresses personal autonomy in health choices, advancements like E. coli-derived mini circles, and the exciting potential of stem cell treatments for various health issues.

57 snips
Oct 17, 2023 • 1h 5min
Flex on ‘Em: Why You Should Build Life-Extending Skeletal Muscle Mass – Dr. Gabrielle Lyon : 1097
Dr. Gabrielle Lyon, a geriatrician and author of Forever Strong, dives into the transformative power of muscle mass for longevity. She debunks myths around plant-based diets, advocating instead for protein from animal sources to drive health and fitness. The conversation touches on the critical role of strength training, the challenges of maintaining muscle with aging, and innovative dietary strategies to enhance muscle health. Lyon stresses the importance of informed eating habits and muscle-centric medicine for a longer, healthier life.

16 snips
Oct 12, 2023 • 50min
Chilling Secrets: Unlocking Cold-Water Therapy's Power with Dr. Mark Harper : 1096
Dr. Mark Harper, an anesthetist and researcher with expertise in cold-water therapy, discusses the remarkable benefits of cold immersion in treating conditions like depression and arthritis. He shares practical tips for safely starting your own cold-water practice, including ideal plunge frequency and the unique effects of face immersion. The conversation also dives into how sauna use complements cold exposure and the importance of community in enhancing the experience. Harper's insights are backed by research, making a compelling case for the therapeutic power of chilling.

Oct 10, 2023 • 55min
Unlocking Breast Cancer Resilience: The Impact of Shame, Love & Holistic Healing - Dr. Toni Galardi : 1095
Dr. Toni Galardi, a holistic psychotherapist and a breast cancer survivor, shares her inspiring journey and insights on healing. She discusses the critical mind-body connection and how emotions can influence health outcomes. Delving into alternative healing methods, she emphasizes the importance of self-love, personalized nutrition, and community support. Galardi also explores the psychological impacts of societal perceptions on breast health and the intriguing concept of the 'cancer personality.' This conversation offers profound wisdom for anyone interested in health and wellness.

52 snips
Oct 5, 2023 • 1h 16min
Heart Coherence Unveiled: A Journey with Rollin McCraty : 1094
Rollin McCraty, Director of Research at the HeartMath Institute, dives into the fascinating world of heart coherence and its profound effects on health and human connections. He discusses how emotions influence cognitive processes and behaviors, revealing the importance of heart rate variability. Rollin also explores the impact of technology on our biology and how collective human emotions can affect global consciousness. Plus, he shares insights on harnessing heart coherence for personal growth and enhancing experiences at large gatherings.

9 snips
Oct 3, 2023 • 1h 14min
The Key to Longevity & A Workout Routine That Sticks - Tony Horton : 1093
Tony Horton, a renowned motivational speaker and creator of P90X, joins to discuss the key to longevity through tailored workouts for women’s hormonal cycles. He emphasizes the role of humor and mindfulness in enhancing resilience and overall well-being. Horton shares insightful strategies for injury prevention and the benefits of incorporating cold exposure in fitness routines. The conversation also touches on personal stories of overcoming challenges in fitness and entrepreneurship, urging listeners to prioritize movement and laughter for a fulfilling life.

Sep 28, 2023 • 1h 1min
Unconventional Biohacks for More Radiant & Resilient Skin - Rachel Varga : 1092
In this conversation with Rachel Varga, a double board-certified aesthetic nurse specialist, listeners uncover unconventional biohacks for achieving radiant skin. Rachel explores the critical impact of oxidative stress and environmental toxins on skin health, emphasizing detoxification and conscious consumerism. She discusses the psychological connection between skin and confidence, the dangers of harmful ingredients in popular products, and innovative approaches prioritizing internal nourishment over superficial treatments. Her insights challenge traditional skincare wisdom.

Sep 26, 2023 • 1h 26min
Hacking Happiness: How to Leverage Evolutionary Biology to Live the Good Life - Dr. Gad Saad : 1091
Join Dr. Gad Saad, a marketing professor and author renowned for his work in evolutionary behavioral sciences, as he dives into the science of happiness. They explore how happiness can be cultivated as a skill rather than a mere byproduct of life circumstances. Dr. Saad discusses decision-making in relationships and the evolutionary roots of behavior, including insights on male hormonal influences on consumption. He emphasizes the critical role of play and personal choices in fostering joy, blending science with practical advice for a fulfilled life.

11 snips
Sep 21, 2023 • 1h 19min
Unlocking Health Through Your Genetic Code: Healing from Veganism, Chronic Pain & Stressors - Chris Masterjohn : 1090
In this engaging conversation, Chris Masterjohn, a PhD in Nutritional Sciences and former vegan, shares his insights on recovering from the pitfalls of veganism and the impacts of oxalates on health. He delves into the intricate connection between genetics and mitochondrial function, exploring how these factors influence energy metabolism and psychological resilience. Chris discusses personal experiences with chronic pain and anxiety management, emphasizing the importance of tailored nutritional strategies for better health outcomes. Expect humor and profound revelations throughout!

25 snips
Sep 19, 2023 • 1h 13min
Game-Changing Focus: Play the World’s First FDA-Approved Video Game – Dr. Adam Gazzaley : 1089
Dr. Adam Gazzaley, a renowned neuroscientist and founder of Neuroscape, discusses groundbreaking approaches to enhancing focus and treating ADHD. He introduces Endeavor RX, the first FDA-approved video game for pediatric ADHD, showcasing how gaming can sharpen attention. The conversation explores the biological mechanisms of focus, the impact of video games on mental health, and innovative methods for tracking cognitive progress. Gazzaley emphasizes personalized health solutions, merging technology with neuroscience for a future of cognitive enhancement.


