Top experts Dr Thomas Dayspring, Dr William Cromwell, Danny Lennon, Dr Alan Flanagan, and Dr Gil Carvalho discuss ApoB, a crucial marker for heart disease risk. They cover its impact on LDL particles, atherosclerosis, and longevity. The episode explores measuring ApoB, normal levels, causes of elevation, saturated fats, and reliability over LDL cholesterol.

Joining the discussion are Dr. Philip Calder, an expert on polyunsaturated fats, Dr. Gil Carvalho, a nutrition specialist, Prof. Roy Taylor, a pioneer behind the twin-cycle hypothesis, and Dr. Alan Flanagan, who researches dietary fats. They dive into the role of omega-3 and omega-6 fatty acids in inflammation and heart health. The conversation includes insights on the impact of saturated fats and the importance of balance in our diet. They also explore the connection between dietary fat, insulin resistance, and liver health, unraveling common misconceptions along the way.

Last week we featured Part 1 of the best moments from The Proof in 2022, and this week we bring you part 2.Episode #242 is a compilation that mostly focuses on sleep, exercise and planetary health featuring a range of guests from across the year.Guests featured include Drs Dean and Ayesha Sherzai, Dr Alan Flanagan, Dr Andrew Huberman, Dr David Jenkins, Dr Kieron Rooney, Paul Taylor, Fritz Horstmann, Drew Harrisberg and Nicholas Carter.Specifically, we cover: Intro (00:00) Sleep and weight gain with Drew Harrisberg (01:28) Tips for better sleep with Dr. Andrew Huberman (13:00) Manage Craving with Fritz Horstman (15:49) Carnivore Crazy with Drew Harrisberg (39:42) Big Pharma and Big Food with Dr. Alan Flanagan and Drew Harrisberg (49:32) Good stress with Dr. Paul Taylor (59:48) Mitochondria and Longevity with Dr. Kieron Rooney and Drew Harrisberg (1:12:14) Mitochondria and Longevity with Dr. Paul Taylor (1:17:46) Fermented foods (1:24:27) Developing an exercise program with Drew Harrisberg (1:25:18) Improving brain function with Drs. Ayesha and Dean Sherzai (1:41:57) Resistance starch and cancer with Drew Harrisberg (1:55:32) What's causing climate change with Nicolas Carter (2:06:11) Should we eat fish with Dr. David Jenkins (2:11:01) Building new habits with Fritz Horstman (2:12:51) Outro (2:26:46) Episodes featured: Episode #206 with Drew Harrisberg Episode #205 with Dr Andrew Huberman Episode #239 with Fritz Horstmann Episode #203 with Drew Harrisberg Episode #229 with Paul Taylor Episode #226 with Drs Dean and Ayesha Sherzai Episode #223 with Drew Harrisberg Episode #222 with Dr Kieron Rooney Episode #230 with Nicholas Carter Episode #216 with Dr David Jenkins I hope you find this episode helpful for consolidating some of the key learnings from 2022.To make sure you never miss an episode be sure to follow/subscribe on Apple, Spotify and/or YouTube. Whichever platform you prefer to receive notifications from when new episodes of The Proof are released.To check out our sponsors who make this show possible, and enjoy great savings, visit theproof.com/friends.Another way to show your support is to leave a review on the Apple podcast app, or a comment on YouTube - I read all of these.And don’t forget to grab a copy of my new Plant-Based Ferments recipe book - a great way to improve your overall health by encouraging greater microbiome diversity.Enjoy, friends.SimonWant to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.Simon Hill, MSc, BSc (Hons)Creator of theproof.com and host of The Proof with Simon HillAuthor of The Proof is in the PlantsWatch the episodes on YouTube or listen on Apple/SpotifyConnect with me on Instagram, Twitter, and FacebookNourish your gut with my Plant-Based Ferments GuideDownload my complimentary two-week meal plan and high protein Plant Performance recipe book

Dr. Alan Flanagan discusses non-alcoholic fatty liver disease (NAFLD) and its wider health ramifications. Topics include the development and consequences of NAFLD, identifying symptoms, linking it with type 2 diabetes, and strategies for reducing fat accumulation in the liver. They also explore the impact of sugars and dietary fats on fatty liver disease, beneficial dietary patterns for liver health, and the effects of meal frequency on liver fat accumulation. Sleep deprivation's impact on calorie consumption and visceral fat is discussed, along with recommendations for lifestyle modifications.

Dr Alan Flanagan, PhD, and Dr Matthew Nagra, ND, critically examine the bold assertions made by Dr Steven Gundry in his book 'The Plant Paradox.' They discuss the myths vs. facts surrounding lectins, including their role in leaky gut syndrome, inflammation, and weight gain. They debunk misconceptions about lectins triggering various health conditions, analyze the impact of lectin content in foods, and explore studies on antibodies and food allergies. Overall, they advocate for a balanced diet that includes beans and emphasize the lack of evidence supporting adverse effects of consuming lectin-containing foods.