How Fasting Works To Increase Longevity And Prevent Disease

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Mar 25, 2022

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Dr. Valter Longo, an expert in longevity, joins biohacker Dave Asprey and nephrologist Dr. Jason Fung to discuss the transformative power of fasting. They delve into how fasting can reduce inflammation, improve gut health, and aid in cancer treatment. The conversation highlights the biology of fasting, its role in activating autophagy, and the psychological benefits for mental clarity. They explore practical fasting strategies and dietary choices that can enhance longevity and overall health, emphasizing the importance of timing in eating.

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ADVICE

Fasting Mimicking Diet (FMD)

The fasting mimicking diet involves short periods of calorie restriction.
Follow the 800–1100 calorie diet for five days, a few times yearly.

INSIGHT

FMD's Drug-Like Effects

FMD mimics the effects of multiple drugs simultaneously, impacting insulin, glucose, IGF-1, and leptin levels.
No drug can achieve the combined effects of this diet.

INSIGHT

FMD Macronutrients

The FMD is high in healthy fats and carbohydrates from vegetables and nuts but low in protein and legumes.
This combination offers potent effects while minimizing long-term risks from extreme dietary shifts.

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This episode is brought to you by Athletic Greens, ButcherBox, and Rupa Health.

Fasting has numerous proven benefits to optimize health. It can help reduce inflammation, brain fog, and insulin resistance. It can also increase energy and bone density, activate autophagy—the process of cleaning out damaged cells—and reduce the signs of aging. The food we eat has an amazing ability to heal, but the timing of when we eat or abstain from eating can also have profound impacts on our health.

In today’s episode, I talk with Dr. Valter Longo, Dave Asprey, and Dr. Jason Fung about the mechanisms behind fasting, why most of us can benefit from fasting, and how fasting can be a useful tool in cancer treatment.

Dr. Valter Longo is an internationally recognized leader in the field of aging studies and related diseases. Valter is the author of an extraordinary book, The Longevity Diet. The culmination of 25 years of research on aging, nutrition, and disease across the globe, it provides an easy-to-understand, accessible, and implementable road map to living well longer through improved nutrition.

Dave Asprey is the creator of the Bulletproof Diet and innovator of Bulletproof Coffee. Over the last two decades Dave, the “Father of Biohacking,” has worked with world-renowned doctors, researchers, scientists, and global mavericks to uncover the latest, most innovative methods, techniques, and products for enhancing mental and physical performance.

Dr. Jason Fung is a physician, author, and researcher. His groundbreaking, science-based books about diabetes and obesity—The Diabetes Code, The Obesity Code, and The Complete Guide to Fasting—have sold over one million copies and challenged the conventional wisdom that diabetics should be treated with insulin. His latest book is The Cancer Code: A Revolutionary New Understanding of a Medical Mystery.

This episode is brought to you by Athletic Greens, ButcherBox, and Rupa Health.

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Full-length episodes of these interviews can be found here:

Dr. Valter Longo

Dave Asprey

Dr. Jason Fung