Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

Episode 10: IV Induction Agents

Jul 19, 2016
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ADVICE

Engage via Website Comments

  • Leave comments on the ACCRAC website to share thoughts and spark discussions.
  • Group discussions help everyone learn better than isolated comments.
INSIGHT

IV Anesthetics Bind GABA-A Receptor

  • Most IV anesthetics, except ketamine, act primarily on the GABA-A receptor.
  • Propofol potentiates GABA at low doses and activates it directly at high doses.
ADVICE

Manage Infusion Duration Smartly

  • Understand context sensitive half-time to manage infusion duration and wake-up times.
  • Longer infusions can prolong drug clearance and recovery time of medications like diazepam.
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