Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast cover image

Episode 10: IV Induction Agents

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

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Contect Sensitive Half Time

Probopha is a competitive inhibitor of c y p three a four. One way that you'll see this manifested, that you might be asked about, is it can increase the duration of action of medazilam. It has a context sensitive half time of ten minutes for infusions up to three hours, and then still less than forty minutes forinfusions of three to eight hours.

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