Paul Saladino MD podcast 250. When You Should Worry About LDL Cholesterol with Mike Fave
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Jul 19, 2024 Mike Fave, an expert in cholesterol and cardiovascular health, discusses various topics with Paul including gene mutations, downsides of lowering LDL, money in statins, PCSK9 Inhibitors, and primary vs. secondary prevention in cardiovascular disease. They explore the complexities of lipid lowering drugs and offer insights into understanding true risks for heart attacks.
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Comprehensive Cardiovascular Risk Assessment
- If your doctor only checks LDL cholesterol, ask for more comprehensive blood work.
- Request tests like fasting insulin, hs-CRP, and other markers to assess cardiovascular risk.
LDL, ApoB, and Atherosclerosis: Context Matters
- LDL cholesterol and ApoB do not always correlate with atherosclerosis, especially in metabolically healthy individuals.
- This challenges the mainstream view that LDL directly causes heart disease.
Dave Feldman's Lean Mass Hyper-Responders Study
- Dave Feldman's study on lean mass hyper-responders showed no correlation between high LDL and heart disease.
- This challenges the notion that high LDL on a low-carb diet is inherently dangerous.