The chapter sheds light on the challenges surrounding the long-term efficacy and potential negative effects of cholesterol-lowering drugs like bambatoic acid, PCSK9 inhibitors, azetamide, and statins due to limited data. It emphasizes the need for unbiased information free from pharmaceutical influence and explores the impact of meta-analyses on hiding poorly conducted studies, discussing diverse factors influencing LDL cholesterol levels and suggesting lifestyle changes as alternatives to medication dependence.

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